Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450492 | 0.89 | NPC1 (0.59) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL27248745 | 0.89 | KMT2A (0.53) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL5924443 | 0.88 | ESR1 (0.69) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL308624 | 0.88 | KMT2A (0.52) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2655338 | 0.87 | KMT2A (0.57) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL13011084 | 0.84 | ESR1 (0.60) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL8729045 | 0.84 | ESR1 (0.60) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6806977 | 0.84 | KMT2A (0.54) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL10606064 | 0.83 | KMT2A (0.53) | KMT2ANPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4632930 | 0.83 | NPC1 (0.59) | KMT2ANPC1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145046-A1 | 6-ETHER/THIOETHER-PURINES AS TOPOISOMERASE II CATALYTIC INHIBITORS AND THEIR USE IN THERAPY | CLINIGEN GROUP PLC (GB) | 2017-05-25 | — | — | US | disclosed |
| US-6815567-B2 | MANUFACTURING OF MOLECULAR ELECTRONIC DEVICE, NITRATION, ESTERIFICATION, HYDROLYSIS, SULFIDING | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2004-11-09 | — | — | US | disclosed |
| US-20040147786-A1 | Derivatives of 4-sulfanylalkyl-3,5-dinitrobenzyl alcohol and method for preparing the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147786-A1 | Derivatives of 4-sulfanylalkyl-3,5-dinitrobenzyl alcohol and method for preparing the same | ADH1A, ADH1C, ADH5 | KMT2A 1744/4885NPC1 2831/4885ALDH1A1 6/4885 |
| US-20170145046-A1 | 6-ETHER/THIOETHER-PURINES AS TOPOISOMERASE II CATALYTIC INHIBITORS AND THEIR USE IN THERAPY | TOP2A, TOP1, TOP2B | KMT2A 2795/4885NPC1 2358/4885ALDH1A1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.