Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763631 | 0.92 | EPHX2 (0.48) | EPHX2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6858927 | 0.92 | EPHX2 (0.48) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL1323193 | 0.92 | EPHX2 (0.48) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL31171976 | 0.83 | EPHX2 (0.38) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL18411712 | 0.82 | HSD11B1 (0.46) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL24728074 | 0.80 | GRIN2D (0.52) | EPHX2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6865283 | 0.80 | GRIN2D (0.52) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL6159216 | 0.80 | GRIN2D (0.52) | EPHX2ALDH1A1KDM4EHTTGRIN2D | |
| SCHEMBL2438575 | 0.80 | POLB (0.50) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL1758579 | 0.78 | GRIN2D (0.53) | EPHX2ALDH1A1KDM4EHTTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138828-A2 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |