Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789599 | 1.00 | KMT2A (0.50) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3780965 | 0.94 | ALDH1A1 (0.56) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3780968 | 0.94 | ALDH1A1 (0.56) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3787349 | 0.92 | ALDH1A1 (0.49) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3780243 | 0.88 | LMNA (0.52) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3780235 | 0.88 | LMNA (0.52) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3779982 | 0.85 | GAA (0.52) | KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL3779984 | 0.85 | GAA (0.52) | KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL3791119 | 0.84 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL3791117 | 0.84 | KMT2A (0.49) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116526-A1 | DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2009-11-11 | — | — | EP | claimed |
| WO-2010083537-A2 | OPTIMAL BIOLOGICAL MARKER FOR THE BIOLOGICAL POTENCY OF EMBLICA OFFICINALIS GAERTN. (AMLA) FRUIT-METHODS AND PRODUCTS THEREOF | SAMI LABS LIMITED (IN) | 2010-07-22 | — | — | WO | disclosed |
| EP-2116526-A1 | DERIVATES OF SUBSTITUTED TARTARIC AICD AND USAGE FOR PREPARATING BETA SECRETASE INHIBITORS | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2009-11-11 | — | — | EP | disclosed |