Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ME2 | P23368 | 1/20 | 0.51 |
| ▸ | ME1 | P48163 | 1/20 | 0.51 |
| ▸ | ME3 | Q16798 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709870 | 0.92 | MAPT (0.61) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5464809 | 0.91 | NAMPT (0.57) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3124993 | 0.90 | MAPT (0.58) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3114683 | 0.89 | MAPT (0.57) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23355487 | 0.87 | MAPT (0.61) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3807661 | 0.87 | MAPT (0.64) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19212323 | 0.86 | MAPT (0.60) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5573222 | 0.85 | MAPT (0.76) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22776398 | 0.85 | MAPT (0.58) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1136833 | 0.84 | MAPT (0.64) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |