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SCHEMBL3124993

SCHEMBL3124993

CC(C)(C)OC(=O)N1CCN(c2ccc(CCCO)cc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.58
▸ LMNA P02545 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ SMN1; SMN2 Q16637 4/20 0.57
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ HTT P42858 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ ESRRB O95718 1/20 0.56
▸ ESR1 P03372 1/20 0.56
▸ ESRRA P11474 1/20 0.56
▸ ESRRG P62508 1/20 0.56
▸ DDB1 Q16531 1/20 0.53
▸ CRBN Q96SW2 1/20 0.53
▸ GPR119 Q8TDV5 9/20 0.52
▸ NAMPT P43490 1/20 0.51
▸ TSHR P16473 1/20 0.48
▸ NR1H2 P55055 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23355487 0.92 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3785257 0.90 MAPT (0.58) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3114683 0.89 MAPT (0.57) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3709870 0.87 MAPT (0.61) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL1136833 0.87 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL19212323 0.86 MAPT (0.60) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL5573222 0.85 MAPT (0.76) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL3807661 0.84 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL4826310 0.83 SIGMAR1 (0.54) MAPTLMNAALDH1A1SMN1; SMN2MEN1
SCHEMBL20306312 0.83 MAPT (0.62) MAPTLMNAALDH1A1SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 — — US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 — — US disclosed
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2022-09-15 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
EP-2474525-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-15 — — EP disclosed
EP-2474523-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-08 — — EP disclosed
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-29 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474523-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474525-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474523-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
EP-2114873-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION Lantheus Medical Imaging, Inc. (US) 2009-11-11 — — EP disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010631-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-11241509-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 MAPT 1322/4885LMNA 1194/4885ALDH1A1 662/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 MAPT 1201/4885LMNA 1041/4885ALDH1A1 798/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 MAPT 4188/4885LMNA 3406/4885ALDH1A1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.