SCHEMBL3785300

SCHEMBL3785300

C=C(C)C(=O)Oc1ccc(Cl)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.49
TDP1 Q9NUW8 3/20 0.49
TSHR P16473 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPT P10636 2/20 0.45
TTR P02766 3/20 0.44
HPGD P15428 3/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
PGR P06401 1/20 0.44
HSP90AA1 P07900 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
HSPA5 P11021 1/20 0.44
CBR1 P16152 1/20 0.44
TBXA2R P21731 1/20 0.44
SLC6A2 P23975 1/20 0.44
AGTR1 P30556 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30970223 0.89 TTR (0.52) KMT2ATDP1L3MBTL1MAPTTTR
SCHEMBL677375 0.89 TTR (0.52) KMT2ATDP1L3MBTL1MAPTTTR
SCHEMBL28437072 0.87 KMT2A (0.54) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL618918 0.87 TDP1 (0.56) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL31572520 0.87 TDP1 (0.56) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL11221300 0.86 CFD (0.42) KMT2AMEN1
SCHEMBL9776666 0.84 KMT2A (0.50) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL9544939 0.83 L3MBTL1 (0.51) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL134715 0.83 KMT2A (0.57) KMT2AMEN1TDP1TSHRL3MBTL1
SCHEMBL21328026 0.81 KMT2A (0.55) KMT2AMEN1TDP1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP claimed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US claimed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP claimed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO claimed
CN-113200856-B Trifluoromethyl propylene compound and preparation method and application thereof 南京工业大学 2022-06-07 CN disclosed
CN-113200856-A Trifluoromethyl propylene compound and preparation method and application thereof 南京工业大学 2021-08-03 CN disclosed
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP disclosed
EP-1917236-B1 CHROMOPHORIC POLYMER MEMPILE INC (US) 2010-08-18 EP disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
US-20080197322-A1 ADDITIVES AND COMONOMERS FOR THE ENHANCEMENT OF POLYMER PROPERTIES MEMPILE INC. (US) 2008-08-21 US disclosed
EP-1917236-A1 CHROMOPHORIC POLYMER Mempile Inc. (US) 2008-05-07 EP disclosed
US-7288360-B2 Image recording material FUJIFILM CORPORATION (JP) 2007-10-30 US disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed
WO-2007010519-A1 CHROMOPHORIC POLYMER MEMPILE INC. (US) 2007-01-25 WO disclosed