Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131722 | 0.82 | THRA (0.43) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL3367291 | 0.79 | THRA (0.41) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL1000960 | 0.79 | THRA (0.41) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL29368397 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL1745934 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL3367289 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL29470540 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL31146900 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL1000962 | 0.76 | KMT2A (0.45) | NPC1RAB9ATHRATHRBLMNA | |
| SCHEMBL5023224 | 0.74 | NPC1 (0.42) | NPC1RAB9ATHRATHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096052-A1 | OXYNTOMODULIN ANALOGS | MERCK SHARP & DOHME CORP. (US) | 2010-08-26 | — | — | WO | disclosed |
| EP-1704167-A1 | A METHOD TO MAKE A PEPTIDE-CARRIER CONJUGATE WITH A HIGH IMMUNOGENICITY | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005058968-A1 | A METHOD TO MAKE A PEPTIDE-CARRIER CONJUGATE WITH A HIGH IMMUNOGENICITY | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-06-30 | — | — | WO | disclosed |