Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 10/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100343 | 0.80 | SCD (0.47) | MEN1KMT2ASCDRECQL | |
| SCHEMBL1236210 | 0.79 | SCD (0.55) | MEN1KMT2ASCD | |
| SCHEMBL16495737 | 0.71 | FFAR2 (0.33) | — | |
| SCHEMBL3715973 | 0.71 | MEN1 (0.56) | MEN1KMT2ASCDRECQL | |
| SCHEMBL3712697 | 0.71 | MEN1 (0.56) | MEN1KMT2ASCDRECQL | |
| SCHEMBL3233566 | 0.70 | SCD (0.57) | MEN1KMT2ASCDRECQL | |
| SCHEMBL4024534 | 0.69 | HPGD (0.76) | MEN1KMT2ARECQL | |
| SCHEMBL16872542 | 0.69 | SCD (0.63) | SCD | |
| SCHEMBL3222620 | 0.69 | LMNA (0.43) | MEN1KMT2ASCDRECQL | |
| Hydrochloric Acid SCHEMBL3791256 | 0.68 | SCD (0.61) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398809-B1 | NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK CANADA INC (CA) | 2015-07-08 | — | — | EP | disclosed |
| EP-2398809-A1 | NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Canada Inc. (CA) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094120-A1 | NOVEL SPIRO COMPOUNDS USEFUL AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-08-26 | — | — | WO | disclosed |