Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912987 | 0.90 | SYK (0.65) | SYK | |
| SCHEMBL3791847 | 0.90 | SYK (0.63) | SYK | |
| SCHEMBL3800518 | 0.88 | SYK (0.58) | SYK | |
| SCHEMBL913094 | 0.79 | SYK (0.67) | SYK | |
| SCHEMBL913775 | 0.78 | SYK (0.61) | SYK | |
| SCHEMBL2627289 | 0.77 | SYK (0.69) | SYK | |
| SCHEMBL1354244 | 0.76 | SYK (1.00) | SYK | |
| SCHEMBL22135700 | 0.76 | SYK (0.57) | SYK | |
| SCHEMBL3790334 | 0.76 | JAK3 (0.60) | SYK | |
| SCHEMBL20760027 | 0.75 | SYK (0.57) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129802-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | claimed |
| WO-2010129802-A1 | INHIBITORS OF JAK | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |