Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181995 | 0.83 | NPC1 (0.36) | OPRM1OPRK1OPRD1 | |
| SCHEMBL3786554 | 0.79 | OPRM1 (0.32) | OPRM1OPRK1ALDH1A1LMNAOPRD1 | |
| SCHEMBL3704054 | 0.74 | SLC6A9 (0.47) | — | |
| Hydrochloric Acid SCHEMBL3705815 | 0.72 | SLC6A9 (0.35) | — | |
| SCHEMBL3706848 | 0.68 | SLC6A9 (0.62) | — | |
| SCHEMBL7895340 | 0.68 | SLC6A9 (0.62) | — | |
| SCHEMBL3710881 | 0.66 | CNR2 (0.40) | OPRM1LMNA | |
| SCHEMBL3710931 | 0.65 | OPRM1 (0.31) | OPRM1OPRD1 | |
| SCHEMBL4241763 | 0.65 | SLC6A9 (0.34) | OPRM1OPRK1OPRD1 | |
| SCHEMBL4238324 | 0.65 | SLC6A9 (0.34) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |