Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.64 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16787409 | 0.85 | CTSK (0.48) | CTSKATMCTSSCTSBKMT2A | |
| SCHEMBL6616311 | 0.85 | CTSK (0.60) | CTSKCACNA1BATMCTSSALDH1A1 | |
| SCHEMBL7539112 | 0.85 | CTSK (0.60) | CTSKCACNA1BATMCTSSALDH1A1 | |
| SCHEMBL2825910 | 0.84 | CTSK (0.60) | CTSKATMCTSSCTSBCTSL | |
| SCHEMBL2825914 | 0.84 | CTSK (0.60) | CTSKATMCTSSCTSBCTSL | |
| SCHEMBL30376528 | 0.84 | CTSK (0.60) | CTSKATMCTSSCTSBCTSL | |
| SCHEMBL1519799 | 0.84 | CTSL (0.60) | CTSKATMCTSSCTSBCTSL | |
| SCHEMBL1519803 | 0.84 | CTSL (0.60) | CTSKATMCTSSCTSBCTSL | |
| SCHEMBL31407583 | 0.84 | CACNA1B (0.52) | CTSKCACNA1BTAAR1CTSSCTSB | |
| SCHEMBL1094506 | 0.83 | ATM (0.62) | CTSKATMCTSSCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024762-A1 | PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES | ORGANOCLICK AKTIEBOLAG (SE) | 2010-03-04 | — | — | WO | disclosed |