SCHEMBL378660

SCHEMBL378660

Oc1cccc2c1nnn2O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.41
ACHE P22303 1/20 0.40
KCNMA1 Q12791 3/20 0.38
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
METAP2 P50579 2/20 0.36
MMP2 P08253 2/20 0.36
RAB9A P51151 2/20 0.36
CHRM1 P11229 1/20 0.36
COMT P21964 1/20 0.36
ADRA1A P35348 1/20 0.36
METAP1 P53582 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL3673310 0.98 POLB (0.48) POLBMAPK1ATMMAPTLMNA
SCHEMBL9268431 0.83 MAPK1 (0.47) POLBMAPK1ATMMAPTLMNA
SCHEMBL8146888 0.78 MAPT (0.48) MAPTLMNAACHEKCNMA1ALDH1A1
SCHEMBL3282850 0.78 GRM2 (0.50) POLBMAPK1ATMMAPTLMNA
SCHEMBL1154415 0.78 MAPK1 (0.48) POLBMAPK1ATMMAPTLMNA
SCHEMBL10734042 0.78 SLC9A1 (0.48) MAPTLMNAACHEKCNMA1ALDH1A1
SCHEMBL8425686 0.78 ACHE (0.39) POLBMAPK1ATMMAPTLMNA
SCHEMBL2113290 0.78 MAPK1 (0.48) POLBMAPK1ATMMAPTLMNA
SCHEMBL2670682 0.78 POLB (0.48) POLBMAPK1ATMMAPTLMNA
SCHEMBL3767410 0.78 ACHE (0.39) MAPTLMNAACHEKCNMA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3577466-B1 REAGENT FOR MASS SPECTROMETRY ROCHE DIAGNOSTICS GMBH (DE) 2026-01-07 EP claimed
EP-3974879-B1 OPTICAL SHEET AND PROCESS FOR FORMING THE OPTICAL SHEET SK MICROWORKS SOLUTIONS CO LTD (KR) 2025-09-10 EP claimed
CN-115518156-B Nanocomposite capable of releasing near-infrared thermic agent in response manner, preparation method and application 西安交通大学医学院第二附属医院 2023-10-10 CN claimed
EP-3630738-B1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2023-07-19 EP claimed
EP-3634944-B1 SYNTHESIS OF TYROSINE DERIVED DIPHENOL MONOMERS MEDTRONIC INC (US) 2022-06-29 EP claimed
EP-2941435-B1 MANNOSE-RECEPTOR SELECTIVE LYSINYLATED CATIONIC AMPHIPHILES AND A PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2021-06-16 EP claimed
EP-3150609-B1 PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES INTELLIKINE LLC (US) 2018-09-12 EP claimed
EP-3016935-B1 PROCESS FOR THE PREPARATION OF INTERMEDIATE OF DOLUTEGRAVIR HETERO RESEARCH FOUNDATION (IN) 2018-09-05 EP claimed
EP-3089985-B1 SILICON-BASED FUNGICIDES AND PROCESS FOR PRODUCING THE SAME COUNCIL SCIENT IND RES (IN) 2018-06-27 EP claimed
EP-2708538-B1 Process for preparing fused pyrimidine-dione derivatives, useful as as TRPA1 modulators GLENMARK PHARMACEUTICALS SA (CH) 2015-08-12 EP claimed
EP-0564739-B1 Backbone cyclic peptides, processes for their preparation and pharmaceutical compositions containing them YISSUM RES DEV CO (IL) 2000-01-26 EP claimed
EP-0624582-A1 Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1994-11-17 EP claimed
EP-0355266-B1 APPARATUS FOR PERFORMING REPETITIVE CHEMICAL REACTIONS MILLIPORE CORPORATION (US) 1993-06-09 EP claimed
EP-0296059-B1 TRIPEPTIDES WITH A POLYCYCLIC NITROGEN STRUSTURE, THEIR PROCESS OF PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS THEREOF ADIR ET COMPAGNIE (FR) 1992-03-18 EP claimed
EP-0305297-A1 Derivatives of aza-z-bicyclooctane-caboxylicacid-3, processes for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1989-03-01 EP claimed
EP-0296059-A1 Tripeptides with a polycyclic nitrogen strusture, their process of preparation and the pharmaceutical compositions thereof ADIR ET COMPAGNIE (FR) 1988-12-21 EP claimed
EP-0262053-A2 Amino-acid derivatives, their preparation and pharmaceutical compositions containing them CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1988-03-30 EP claimed
EP-0064714-B1 PROCESS FOR DESENSITIZING HYDROXYBENZOTRIAZOLES AND HYDROXY-OXOBENZOTRIAZINES HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-21 EP claimed
EP-0017536-B1 PROCESS FOR THE PREPARATION OF SOMATOSTATINE SANOFI S.A. (FR) 1983-03-23 EP claimed
EP-0017536-A2 Process for the preparation of somatostatine SANOFI S.A. (FR) 1980-10-15 EP claimed