Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880010 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL19199299 | 0.91 | HSD17B1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL2848482 | 0.90 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL6559203 | 0.88 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL25829686 | 0.87 | ESR1 (0.41) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL22708077 | 0.87 | HSD17B1 (0.53) | ALDH1A1HSD17B10CYP1B1CYP1A2ALOX5 | |
| SCHEMBL23823625 | 0.86 | CYP1A2 (0.44) | ALDH1A1CYP1B1CYP2A6CYP1A2HPGD | |
| SCHEMBL25829126 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 | |
| SCHEMBL29330637 | 0.86 | HSD17B1 (0.49) | ALDH1A1HSD17B10CYP1B1CYP1A2ALOX5 | |
| SCHEMBL7653304 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HIF1ACYP1B1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, ELAVL1, EPCAM | ALDH1A1 336/4885HSD17B10 2767/4885HIF1A 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.