Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 18/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786741 | 0.90 | AAK1 (0.45) | HDAC2HDAC1HDAC3BRD9AAK1 | |
| SCHEMBL3790650 | 0.86 | HDAC2 (0.65) | HDAC2HDAC1HDAC3 | |
| SCHEMBL3790541 | 0.82 | CYP17A1 (0.50) | HDAC2HDAC1HDAC3 | |
| SCHEMBL3789925 | 0.82 | HDAC2 (0.51) | HDAC2HDAC1HDAC3AAK1 | |
| SCHEMBL3783723 | 0.82 | BRD9 (0.47) | HDAC2HDAC1HDAC3BRD9 | |
| SCHEMBL3785736 | 0.82 | BRD4 (0.53) | HDAC2HDAC1HDAC3 | |
| SCHEMBL3791592 | 0.82 | HDAC2 (0.51) | HDAC2HDAC1HDAC3AAK1 | |
| SCHEMBL211033 | 0.81 | HDAC1 (0.52) | HDAC2HDAC1HDAC3BRD9 | |
| SCHEMBL29353000 | 0.81 | HDAC1 (0.52) | HDAC2HDAC1HDAC3BRD9 | |
| SCHEMBL3788603 | 0.80 | HSP90AA1 (0.46) | HDAC2HDAC1HDAC3BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | HDAC2 549/4885HDAC1 1686/4885HDAC3 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.