Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618305 | 0.92 | KMT2A (0.65) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL28051621 | 0.87 | KMT2A (0.45) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL31570070 | 0.87 | IKBKB (0.71) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL3792022 | 0.87 | IKBKB (0.71) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL18070541 | 0.85 | KDM4E (0.53) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL3791264 | 0.85 | PPM1B (0.50) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL3781881 | 0.84 | MCL1 (0.57) | KMT2AKDM4EGFERRXFP1IKBKB | |
| SCHEMBL1682394 | 0.84 | KMT2A (0.63) | KMT2AKDM4EGFERRXFP1TDP1 | |
| SCHEMBL31268209 | 0.84 | KMT2A (0.63) | KMT2AKDM4EGFERRXFP1TDP1 | |
| SCHEMBL3794862 | 0.82 | IKBKB (0.76) | KMT2AKDM4EGFERRXFP1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-0454590-B1 | Polyimide optical waveguide | NIPPON TELEGRAPH & TELEPHONE (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5108201-A | From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1992-04-28 | — | — | US | disclosed |
| EP-0454590-A2 | Polyimide optical waveguide | NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4129736-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4082739-A | FIBRE-REACTIVE DYESTUFF CONTAINING A BIS-TRIAZINYLAMINO | CIBA-GEIGY AG (CH) | 1978-04-04 | — | — | US | disclosed |
| US-4079051-A | 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4033944-A | Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-3947407-A | ANTHRAQUINONE DYE | CIBA-GEIGY AG (CH) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KMT2A 1474/4885KDM4E 2606/4885GFER 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.