Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846818 | 0.83 | IGF1R (1.00) | IGF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1250598 | 0.83 | IGF1R (1.00) | IGF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1250596 | 0.83 | IGF1R (1.00) | IGF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7463867 | 0.78 | PIM1 (0.68) | IGF1RCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL4014115 | 0.77 | MEN1 (1.00) | IGF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4014118 | 0.77 | MEN1 (1.00) | IGF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7464574 | 0.77 | PIM1 (0.68) | IGF1RMAPTHPGDHTTCSNK2A2 | |
| SCHEMBL4156417 | 0.75 | CSNK2A2 (0.65) | MEN1KMT2AMAPTHPGDLMNA | |
| SCHEMBL7459912 | 0.73 | GSK3B (0.71) | IGF1RMAPTLMNACSNK2A2CLK1 | |
| SCHEMBL7466029 | 0.73 | CSNK2A1 (0.71) | MEN1KMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082212-A2 | N-BIPHENYLACYL THIAZOLIDINE-2,4-DIONE DERIVATIVES, THEIR SYNTHESIS AND USES | ELDER PHARMACEUTICALS LTD (IN) | 2010-07-22 | — | — | WO | disclosed |