Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 6/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15458896 | 1.00 | PPARA (0.53) | PPARAATMPPARGSLC1A3SLC1A2 | |
| SCHEMBL12486609 | 1.00 | PPARA (0.53) | PPARAATMPPARGSLC1A3SLC1A2 | |
| SCHEMBL12964906 | 0.87 | CYP2C19 (0.52) | ATMSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL7099862 | 0.85 | PPARA (0.58) | PPARAATMPPARGSLC1A3SLC1A2 | |
| SCHEMBL7099865 | 0.85 | PPARA (0.58) | PPARAATMPPARGSLC1A3SLC1A2 | |
| SCHEMBL15607164 | 0.84 | CTSK (0.46) | PPARAATMPPARGCTSSCTSK | |
| SCHEMBL4454869 | 0.82 | CTSK (0.45) | PPARAATMPPARGMEN1KMT2A | |
| SCHEMBL27792966 | 0.82 | CTSK (0.45) | PPARAATMPPARGMEN1KMT2A | |
| SCHEMBL18427972 | 0.81 | PPARA (0.52) | PPARAATMPPARGSLC1A3SLC1A2 | |
| SCHEMBL13002887 | 0.81 | SYK (0.49) | PPARAATMPPARGCTSSSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829210-B2 | Process for preparing docetaxel and its hydrate | SHILPA MEDICARE LIMITED (IN) | 2014-09-09 | — | — | US | disclosed |
| US-20140039209-A1 | PROCESS FOR PREPARING DOCETAXEL AND ITS HYDRATE | SHILPA MEDICARE LIMITED (IN) | 2014-02-06 | — | — | US | disclosed |
| WO-2010024762-A1 | PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES | ORGANOCLICK AKTIEBOLAG (SE) | 2010-03-04 | — | — | WO | disclosed |
| US-6114550-A | Method for the stereo-selective preparation of a derivative of β-phenyl-isoserine and its use in the preparation of taxane derivatives | RHONE-POULENC RORER S.A. (FR) | 2000-09-05 | — | — | US | disclosed |
| US-5726346-A | Process for the stereoselective preparation of a β-phenylisoserine derivative and its use for the preparation of taxane derivatives | RHONE-POULENC RORER S.A. (FR) | 1998-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039209-A1 | PROCESS FOR PREPARING DOCETAXEL AND ITS HYDRATE | TXLNA, EBP, CYP8B1 | PPARA 1426/4885ATM 1969/4885PPARG 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.