Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792966 | 1.00 | CTSK (0.45) | CTSKCTSSPPARAATMALDH1A1 | |
| SCHEMBL15607164 | 0.86 | CTSK (0.46) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL9206058 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ATAAR1 | |
| SCHEMBL9214743 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ATAAR1 | |
| SCHEMBL3787393 | 0.82 | PPARA (0.53) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL15458896 | 0.82 | PPARA (0.53) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL12486609 | 0.82 | PPARA (0.53) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL8529886 | 0.81 | CTSK (0.45) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL9293004 | 0.81 | CTSK (0.45) | CTSKCTSSPPARAATMPPARG | |
| SCHEMBL3782920 | 0.81 | CTSK (0.45) | CTSKCTSSPPARAATMPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029563-A1 | SEMI-SYNTHETIC ROUTE FOR THE PREPARATION OF PACLITAXEL, DOCETAXEL AND 10-DEACETYLBACCATIN III FROM 9-DIHYDRO-13-ACETYLBACCATIN III | 6570763 Canada Inc. (CA) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007143839-A1 | SEMI-SYNTHETIC ROUTE FOR THE PREPARATION OF PACLITAXEL, DOCETAXEL AND 10-DEACETYLBACCATIN III FROM 9-DIHYDRO-13-ACETYLBACCATIN III | 6570763 CANADA INC. (CA) | 2007-12-21 | — | — | WO | disclosed |