Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782894 | 0.89 | CCR2 (0.44) | CCR2KCNH2USP2CYP3A4CYP2D6 | |
| SCHEMBL3786935 | 0.84 | CCR2 (0.44) | CCR2KCNH2USP2CYP3A4CYP2D6 | |
| SCHEMBL3788260 | 0.84 | CCR2 (0.45) | CCR2KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3038771 | 0.84 | CCR2 (0.44) | CCR2KCNH2TACR1USP2CYP3A4 | |
| SCHEMBL3023181 | 0.81 | CCR2 (0.45) | CCR2KCNH2TACR1CYP3A4CYP2D6 | |
| SCHEMBL3789678 | 0.81 | CCR2 (0.41) | CCR2KCNH2USP2CYP3A4CYP2D6 | |
| SCHEMBL3779496 | 0.80 | CCR2 (0.42) | CCR2KCNH2MEN1POLBHTT | |
| SCHEMBL3782834 | 0.79 | CCR2 (0.40) | CCR2KCNH2MEN1POLBHTT | |
| SCHEMBL3043761 | 0.79 | CCR2 (0.45) | CCR2KCNH2TACR1USP2CYP3A4 | |
| SCHEMBL3029490 | 0.79 | NPSR1 (0.49) | CCR2KCNH2L3MBTL1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CYTOPATHFINDER, INC. (JP) | 2010-12-30 | — | — | US | claimed |
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CYTOPATHFINDER, INC. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331298-A1 | Carboxamide Compounds and Their Use | CCR2, CCR1, CCR5 | CCR2 1/4885KCNH2 4417/4885MEN1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.