Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.57 |
| ▸ | ABL1 | P00519 | 10/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | HCK | P08631 | 2/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | PRKDC | P78527 | 2/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.57 |
| ▸ | BLK | P51451 | 3/20 | 0.56 |
| ▸ | BTK | Q06187 | 3/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | JAK3 | P52333 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.55 |
| ▸ | FYN | P06241 | 3/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.55 |
| ▸ | RET | P07949 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23692504 | 0.85 | SRC (0.44) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL24005647 | 0.84 | SRC (0.53) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL13020110 | 0.81 | SRC (0.53) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL21372077 | 0.81 | SRC (0.41) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL13019879 | 0.81 | SRC (0.58) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL3782929 | 0.81 | SRC (0.58) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL3779332 | 0.80 | SRC (0.62) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL13019650 | 0.80 | SRC (0.64) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL3788099 | 0.80 | SRC (0.57) | SRCABL1EGFRKDRMTOR | |
| SCHEMBL13019894 | 0.79 | SRC (0.53) | SRCABL1EGFRKDRMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2020-04-02 | — | — | US | disclosed |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2019-09-19 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230196-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | SRC 3775/4885ABL1 2703/4885EGFR 2568/4885 |
| US-20190284216-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | SRC 3775/4885ABL1 2703/4885EGFR 2568/4885 |
| US-20230382932-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | SRC 3775/4885ABL1 2703/4885EGFR 2568/4885 |
| US-20200102334-A1 | Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | SRC 3775/4885ABL1 2703/4885EGFR 2568/4885 |
| US-10968242-B2 | Cyclopentane-based modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | SRC 3775/4885ABL1 2703/4885EGFR 2568/4885 |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | SRC 1332/4885ABL1 1725/4885EGFR 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.