SCHEMBL378889

SCHEMBL378889

BrCc1cccc(I)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29411735 1.00
SCHEMBL3127217 0.81 TDP1 (0.52)
SCHEMBL348159 0.81 ALDH1A1 (0.61)
SCHEMBL2213709 0.81 ALDH1A1 (0.61)
SCHEMBL9352538 0.79 IDO1 (0.58)
SCHEMBL7600124 0.78 IDO1 (0.47)
SCHEMBL2404811 0.77
SCHEMBL283667 0.77
SCHEMBL28768660 0.77
Benzyl Bromide SCHEMBL3032661 0.77 TSHR (0.74)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586440-B Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-04-09 CN claimed
CN-117586440-A Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-02-23 CN claimed
CN-115975616-B Borehole wall stabilizer and preparation method and application thereof 中石化石油工程技术服务有限公司 2023-12-26 CN claimed
CN-115975616-A Borehole wall stabilizer and preparation method and application thereof 中石化石油工程技术服务有限公司 2023-04-18 CN claimed
CN-112522836-A Gauze fabric prepared from flame-retardant three-proofing fibers and preparation process thereof 安徽和邦纺织科技有限公司 2021-03-19 CN claimed
CN-108299383-A The method of palladium chtalyst one pot process oil-source rock correlation 南京邮电大学 2018-07-20 CN claimed
US-12595272-B2 Methods to produce organotin compositions with convenient ligand providing reactants INPRIA CORPORATION (US) 2026-04-07 US disclosed
US-20260049094-A1 METHODS TO PRODUCE ORGANOTIN COMPOSITIONS WITH CONVENIENT LIGAND PROVIDING REACTANTS INPRIA CORP (US) 2026-02-19 US disclosed
US-20260042786-A1 METHODS TO PRODUCE ORGANOTIN COMPOSITIONS WITH CONVENIENT LIGAND PROVIDING REACTANTS INPRIA CORP (US) 2026-02-12 US disclosed
US-12454525-B2 IL4I1 inhibitors and methods of use MERCK SHARP & DOHME LLC (US) 2025-10-28 US disclosed
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
US-20250248975-A1 MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SCHRODINGER, LLC 2025-08-07 US disclosed
CN-120157675-A Pyrazolo six-membered ring derivative and application thereof in medicine 海思科医药集团股份有限公司 2025-06-17 CN disclosed
US-5208259-A Lipoxygenase enzyme inhibitors IMPERIAL CHEMICAL INDUSTRIES (GB) 1993-05-04 US disclosed
US-5137895-A Antiemetic, anxiolytic, gastric emptying and serotonin modulating activity A. H. ROBINS COMPANY, INCORPORATED (US) 1992-08-11 US disclosed
US-5098930-A Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-03-24 US disclosed
EP-0409413-A2 Diaryl ether heterocycles IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-23 EP disclosed
EP-0375404-A2 Heterocyclic derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-27 EP disclosed
US-4328162-A Process for preparing 9,11-unsaturated steroidal compound from the corresponding saturated steroidal compound EASTMAN KODAK COMPANY (US) 1982-05-04 US disclosed
US-4185992-A Imidazole derivatives MAY & BAKER LIMITED (GB) 1980-01-29 US disclosed