SCHEMBL348159

SCHEMBL348159

BrCc1cccc(CBr)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TRPA1 O75762 1/20 0.61
TSHR P16473 1/20 0.61
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP1B1 Q16678 1/20 0.44
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.38
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2213709 1.00 ALDH1A1 (0.61) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
SCHEMBL15389994 0.91 TRPA1 (0.52) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
Methoxymethane SCHEMBL28161427 0.89 TSHR (0.50) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
SCHEMBL30152326 0.87 TRPA1 (0.48) ALDH1A1TRPA1TSHRCYP1A2CYP4F2
SCHEMBL1023596 0.87 ENPP2 (0.50) ALDH1A1TRPA1TSHRENPP2NOS3
SCHEMBL25406688 0.87 TSHR (0.48) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
SCHEMBL1403956 0.87 TRPA1 (0.48) ALDH1A1TRPA1TSHRCYP1A2CYP4F2
SCHEMBL13273601 0.87 TRPA1 (0.48) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
SCHEMBL3526008 0.87 TRPA1 (0.48) ALDH1A1TRPA1TSHRCYP1A1CYP1A2
SCHEMBL28204549 0.87 TDP1 (0.56) ALDH1A1TRPA1TSHRCYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661893-A1 ALPHA-1-MICROGLOBULIN DERIVED PEPTIDE FRAGMENTS AND USES THEREOF Guard Therapeutics International AB (SE) 2025-12-17 EP claimed
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules Belyntic GmbH (DE) 2025-11-18 US claimed
US-20250319443-A1 METHOD FOR MANUFACTURING A THIN-FILM COMPOSITE MEMBRANE FOR WATER TREATMENT, HAVING EXTREME ACID AND ALKALINE STABILITY KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2025-10-16 US claimed
US-20250188151-A1 C-JUN ANTAGONIST PEPTIDES THE UNIVERSITY OF BATH (GB) 2025-06-12 US claimed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
CN-119505222-A Fluorescent antibacterial polymer prepared from natural extract curcumin and application of fluorescent antibacterial polymer in fluorescent fibers 福建师范大学 2025-02-25 CN claimed
EP-4490176-A1 C-JUN ANTAGONIST PEPTIDES The University of Bath (GB) 2025-01-15 EP claimed
CN-119080586-A 1, 3-Dibenzyl phenol compound, preparation method and application thereof in whitening and anti-aging cosmetics 深圳摩尔雾化健康医疗科技有限公司 2024-12-06 CN claimed
CN-118984835-A C-Jun antagonist peptides 巴斯大学 2024-11-19 CN claimed
US-20240368784-A1 METHOD FOR MANUFACTURING A THIN FILM COMPOSITE MEMBRANE FOR ALKALINE WATER ELECTROLYSIS KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2024-11-07 US claimed
US-5348762-A Process for the production of conductive layers CIBA-GEIGY CORPORATION (US) 1994-09-20 US claimed
EP-0285564-B1 ANTISTATIC AND ELECTRICALLY CONDUCTIVE POLYMERS AND MOULDING COMPOSITIONS CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
EP-0260443-B1 NEW MONOMERS AND OLIGOMERS CONTAINING A PLURALITY OF VINYLBENZYL ETHER GROUPS, METHOD FOR THEIR PREPARATION AND CURED PRODUCTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1992-01-08 EP claimed
US-5009812-A Forming charge transfer complexes CIBA-GEIGY CORPORATION (US) 1991-04-23 US claimed
EP-0389359-A1 Process for the preparation of cyclic monofunctionalized tetramines CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1990-09-26 EP claimed
EP-0380236-A2 Organopolysiloxane-polyurea block copolymer and method for its production MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-08-01 EP claimed
EP-0260443-A2 New monomers and oligomers containing a plurality of vinylbenzyl ether groups, method for their preparation and cured products therefrom THE DOW CHEMICAL COMPANY (US) 1988-03-23 EP claimed
US-4707558-A USING A POLAR APPOTIC SOLVENT TO REACT AN ALKALI METAL PHENOXIDE BASED ON A POLYHYDROXY COMPOUND WITH A VINYLBENZYL HALIDE THE DOW CHEMICAL COMPANY (US) 1987-11-17 US claimed
US-4675355-A REACTIVE AMINE-CONTAINING NITROSO COMPOUND AND AN HALOGENATED ALKYLBENZENE TO IMPROVE GREEN STRENGTH; TIRES BRIDGESTONE CORPORATION (JP) 1987-06-23 US claimed
US-4016194-A CATALYTIC CARBONYLATION TEXACO INC. (US) 1977-04-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188151-A1 C-JUN ANTAGONIST PEPTIDES JUN, JUND, FOS ALDH1A1 4745/4885TRPA1 4748/4885TSHR 2744/4885
US-12473328-B2 Method for modification of peptides immobilized on a solid support by traceless reductively cleavable linker molecules PTMS, VIP, HM13 ALDH1A1 2067/4885TRPA1 4766/4885TSHR 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.