Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673536 | 0.87 | CA1 (0.46) | CA1CA2CA9IDO1ALDH1A1 | |
| SCHEMBL11550954 | 0.86 | IDO1 (0.59) | IDO1NPC1RAB9AHTR2ASMN1; SMN2 | |
| SCHEMBL11551499 | 0.84 | IDO1 (0.57) | IDO1NPC1RAB9AHTR2ASMN1; SMN2 | |
| SCHEMBL11550038 | 0.84 | IDO1 (0.57) | IDO1NPC1RAB9AHTR2ASMN1; SMN2 | |
| SCHEMBL11255629 | 0.82 | SIGMAR1 (0.53) | IDO1TDP1MAOAMAOB | |
| SCHEMBL11248744 | 0.82 | SIGMAR1 (0.53) | IDO1TDP1MAOAMAOB | |
| SCHEMBL2129084 | 0.81 | TDP1 (0.46) | CA1CA2CA9IDO1ALDH1A1 | |
| SCHEMBL3792731 | 0.81 | IDO1 (0.48) | CA1CA2CA9IDO1ALDH1A1 | |
| SCHEMBL10701795 | 0.78 | TDP1 (0.47) | CA1CA2CA9IDO1ALDH1A1 | |
| SCHEMBL20710735 | 0.78 | IDO1 (0.50) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262061-B1 | PROCESS FOR STABILIZING CHLORINATION MIXTURES OF PHENOL AND/OR CHLOROPHENOLS | RHONE-POULENC CHIMIE (FR) | 1993-02-24 | — | — | EP | claimed |
| US-4853153-A | USING REDUCING AGENT AND CHLORINATED CYCLIC KETONE | RHONE-POULENC CHIMIE (FR) | 1989-08-01 | — | — | US | claimed |
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2021-08-17 | — | — | US | disclosed |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2019-05-16 | — | — | US | disclosed |
| EP-2075317-B1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE | IDEMITSU KOSAN CO (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-8926857-B2 | Lubricant for compression refrigerating machine and refrigerating apparatus using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8491811-B2 | Lubricant for compression refrigerating machine and refrigerating apparatus using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| EP-2075316-B1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE | IDEMITSU KOSAN CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20100037648-A1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE AND REFRIGERATING APPARATUS USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-20100005829-A1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE AND REFRIGERATING APPARATUS USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2075317-A1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE AND REFRIGERATING APPARATUS USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-4209431-A | OXIDATION AND HEAT RESISTANCE | WITCO CHEMICAL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4181642-A | Process for the production of a glycidyl group containing acrylic resin and its use | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-01-01 | — | — | US | disclosed |
| US-4110306-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof | ARGUS CHEMICAL CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4105627-A | MERCAPTOHETEROCYCLIC RESIN STABILIZERS | ARGUS CHEMICAL CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4086304-A | SALT OF A METAL OF GROUP I OR II AND AN ORGANIC ACID | AKZONA INCORPORATED (US) | 1978-04-25 | — | — | US | disclosed |
| US-4080364-A | Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures | ARGUS CHEMICAL CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-3998782-A | AGAINST HEAT | AKZO N.V. (NL) | 1976-12-21 | — | — | US | disclosed |
| US-3997551-A | OXIDATION RESISTANCE, STABILIZE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | VIPR1, VIP, CYP4A11 | CA1 1540/4885CA2 1244/4885CA9 1563/4885 |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | VIPR1, VIP, CYP4A11 | CA1 1540/4885CA2 1244/4885CA9 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.