Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277519 | 0.87 | IDO1 (0.55) | IDO1NPC1RAB9AFFAR1LMNA | |
| SCHEMBL3792731 | 0.86 | IDO1 (0.48) | TDP1CA1CA2CA9IDO1 | |
| Tromethamine SCHEMBL11426237 | 0.86 | KDM4E (0.51) | TDP1CA1CA2CA9IDO1 | |
| SCHEMBL7341046 | 0.85 | IDO1 (0.48) | IDO1NPC1RAB9AALOX15FFAR1 | |
| SCHEMBL6743777 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 | |
| SCHEMBL7107595 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 | |
| SCHEMBL29036387 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 | |
| SCHEMBL6561009 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 | |
| SCHEMBL11880603 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 | |
| SCHEMBL6462217 | 0.84 | SIGMAR1 (0.50) | TDP1IDO1FFAR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254108-B2 | Laminate structure for biocompatible barrier packaging | RENOLIT SE (DE) | 2022-02-22 | — | — | US | claimed |
| US-20230257619-A1 | Curing of reaction resins using unsaturated peroxides as initiators and organic phosphites as accelerators | RÖHM GMBH (DE) | 2023-08-17 | — | — | US | disclosed |
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2021-08-17 | — | — | US | disclosed |
| CN-110669069-A | Method for preparing diester phosphite by ester exchange | 四川福思达生物技术开发有限责任公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | SHANGHAI AOBO PHARMTECH, INC., LTD. (CN) | 2019-05-16 | — | — | US | disclosed |
| CN-103923119-B | Preparation method and applications of alkyl phosphite | 中蓝连海设计研究院 | 2017-01-11 | — | — | CN | disclosed |
| US-8926857-B2 | Lubricant for compression refrigerating machine and refrigerating apparatus using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-01-06 | — | — | US | disclosed |
| CN-103923119-A | Preparation method and applications of alkyl phosphite | CHINA BLUESTAR LEHIGH ENG CORP | 2014-07-16 | — | — | CN | disclosed |
| US-8491811-B2 | Lubricant for compression refrigerating machine and refrigerating apparatus using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| EP-2075316-B1 | LUBRICANT FOR COMPRESSION REFRIGERATING MACHINE | IDEMITSU KOSAN CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| WO-1996000733-A1 | DIPHOSPHATE OR TRIPHOSPHATE NON-HYDROLYSABLE STABLE ANALOGUES AND METHODS FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-11 | — | — | WO | disclosed |
| US-5250393-A | Containing diazo resin and alkali metal or ammonium silicate | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0492959-A1 | Method for developing presensitized plate for use in making lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 1992-07-01 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0260380-A2 | Liquid polyvinyl chloride resin stabilizer systems based on complexes of organic triphosphites with zinc chloride | Argus Chemical Corporation (US) | 1988-03-23 | — | — | EP | disclosed |
| EP-0188236-A2 | Polyacetal resin compositions having improved resistance to deterioration when exposed to light and containing alkylidene bis(benzotriazolyl phenols) | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1986-07-23 | — | — | EP | disclosed |
| EP-0063180-A1 | Beta-diketone and hydrotalcite stabilizer compositions for halogen-containing polymers and polymer compositions containing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1982-10-27 | — | — | EP | disclosed |
| EP-0047894-A2 | Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins | Argus Chemical Corporation (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0019751-A1 | Condensates from adducts of phosphites and propen-2-oles and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091508-B2 | Fosaprepitant phosphate intermediate and preparation method therefor | VIPR1, VIP, CYP4A11 | TDP1 2721/4885CA1 1540/4885CA2 1244/4885 |
| US-20190144477-A1 | FOSAPREPITANT PHOSPHATE INTERMEDIATE AND PREPARATION METHOD THEREFOR | VIPR1, VIP, CYP4A11 | TDP1 2721/4885CA1 1540/4885CA2 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.