Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | DGKA | P23743 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924320 | 1.00 | TSHR (0.60) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3789355 | 1.00 | TSHR (0.60) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3786088 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3788346 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3786091 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL329741 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3788271 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3790056 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL3788343 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA | |
| SCHEMBL329740 | 0.98 | TSHR (0.58) | TSHRDGKAPAMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501774-B9 | POLYUNSATURATED LINEAR ALDEHYDES AND THEIR DERIVATIVES WITH ANTI-RADICAL ACTIVITY | GIULIANI SPA (IT) | 2010-02-24 | — | — | EP | disclosed |
| EP-1501774-B1 | POLYUNSATURATED LINEAR ALDEHYDES AND THEIR DERIVATIVES WITH ANTI-RADICAL ACTIVITY | GIULIANI SPA (IT) | 2009-08-12 | — | — | EP | disclosed |
| US-20050175555-A1 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity | UNIVERSITA' DELGI STUDI DI MILANO (IT) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050175555-A1 | Polyunsaturated linear aldehydes and their derivatives with anti-radical and anti-tumoral activity | ALOX5, PRDX5, ALOX15 | TSHR 2998/4885DGKA 2233/4885PAM 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.