Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 5/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790221 | 0.83 | CDC25B (0.44) | CSNK2BCSNK2A1PIM1PIM2KDM4E | |
| SCHEMBL3789556 | 0.78 | PIM1 (0.56) | CSNK2BCSNK2A1PIM1PIM2CSNK2A2 | |
| SCHEMBL1312896 | 0.70 | CSNK2A2 (0.55) | CSNK2BCSNK2A1CSNK2A2KDM4EMAPT | |
| SCHEMBL3785494 | 0.70 | PIM1 (0.43) | CSNK2BCSNK2A1PIM1PIM2KDM4E | |
| SCHEMBL13057041 | 0.69 | PIM1 (0.60) | CSNK2BCSNK2A1PIM1PIM2KDM4E | |
| SCHEMBL13056964 | 0.68 | PIM1 (0.50) | CSNK2BCSNK2A1PIM1PIM2KDM4E | |
| SCHEMBL3790215 | 0.68 | PIM1 (0.50) | CSNK2BCSNK2A1PIM1PIM2KDM4E | |
| SCHEMBL13057012 | 0.68 | LCK (0.63) | CSNK2BCSNK2A1PIM1PIM2MAPK8 | |
| SCHEMBL4497415 | 0.68 | L3MBTL1 (0.60) | CSNK2BCSNK2A1CSNK2A2KDM4ETDP1 | |
| SCHEMBL4256425 | 0.65 | FABP4 (0.65) | KDM4ECXCL8TDP1MAPK8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298302-A1 | NOVEL PROTEIN KINASE MODULATORS | SENHWA BIOSCIENCES, INC. (TW) | 2010-11-25 | — | — | US | disclosed |
| WO-2010135571-A1 | NOVEL PROTEIN KINASE MODULATORS | CYLENE PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298302-A1 | NOVEL PROTEIN KINASE MODULATORS | PIM2, PIM1, PIM3 | CSNK2B 91/4885CSNK2A1 57/4885PIM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.