2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL3789760

Sc1nc2ccccc2s1.Sc1nc2ccccc2s1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
HPGD P15428 2/20 0.54
ADRA2A P08913 1/20 0.54
FBP1 P09467 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
DRD2 P14416 1/20 0.54
ALOX15 P16050 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
DRD1 P21728 1/20 0.54
MC5R P33032 1/20 0.54
OPRM1 P35372 1/20 0.54
DRD3 P35462 1/20 0.54
OPRK1 P41145 1/20 0.54
CCR2 P41597 1/20 0.54
HTR6 P50406 1/20 0.54
SLC6A3 Q01959 1/20 0.54
PDK1 Q15118 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL23237 1.00 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL29509878 1.00 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL9813097 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL17684719 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL5811588 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL7640197 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL78798 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL10429471 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL20537310 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL8158663 0.98 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0207737-B1 PROCESS FOR THE STABILIZATION OF MERCAPTOBENZOTHIAZOLE IN A LUBRICATING OIL COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-12-19 EP claimed
EP-3906230-A1 FLUORINE-CONTAINING COMPOUNDS FOR USE AS NUCLEOPHILIC REAGENTS FOR TRANSFERRING FUNCTIONAL GROUPS ONTO HIGH VALUE ORGANIC COMPOUNDS Freie Universität Berlin (DE) 2021-11-10 EP disclosed
CN-112098529-A Fecal metabolite for detecting curative effect of active tuberculosis and detection system thereof 广东省结核病控制中心 2020-12-18 CN disclosed
CN-106661333-B Conductive polymer material and molded article thereof 电化株式会社 2020-10-27 CN disclosed
WO-2020141195-A1 FLUORINE-CONTAINING COMPOUNDS FOR USE AS NUCLEOPHILIC REAGENTS FOR TRANSFERRING FUNCTIONAL GROUPS ONTO HIGH VALUE ORGANIC COMPOUNDS FREIE UNIVERSITÄT BERLIN (DE) 2020-07-09 WO disclosed
US-10629326-B2 Conductive polymer material and molded article using same DENKA COMPANY LIMITED (JP) 2020-04-21 US disclosed
WO-2018055240-A1 PARTICULATE POLYMER COMPOSITION AND METHOD FOR ITS PREPARATION KEMIRA OYJ (FI) 2018-03-29 WO disclosed
US-20170365372-A1 CONDUCTIVE POLYMER MATERIAL AND MOLDED ARTICLE USING SAME DENKA COMPANY LIMITED (JP) 2017-12-21 US disclosed
CN-102993166-B Preparation method and application of 3H-1,2-dithiole-3-thioketone compound UNIV SOOCHOW 2015-05-13 CN disclosed
CN-102993166-A Preparation method and application of 3H-1,2-dithiole-3-thioketone compound UNIV SOOCHOW 2013-03-27 CN disclosed
US-5877238-A Elastomeric compounds incorporating silicon-treated carbon blacks and coupling agents CABOT CORPORATION (US) 1999-03-02 US disclosed
US-5869550-A Method to improve traction using silicon-treated carbon blacks CABOT CORPORATION (US) 1999-02-09 US disclosed
US-5869591-A ELASTOMER COMPRISING CROSSLINKED PSEUDORANDOM INTERPOLYMER OF ALPHA-OLEFIN, VINYLIDENE AROMATIC COMPOUND, OPTIONAL DIENE THE DOW CHEMICAL COMPANY (US) 1999-02-09 US disclosed
US-5830930-A LOWER HYSTERESIS AT HIGH TEMPERATURE AND INCREASED HYSTERESIS AT LOW TEMPERATURE, POOR ABRASION RESISTANCE CABOT CORPORATION (US) 1998-11-03 US disclosed
EP-0822204-A2 Method for the production of nitrile rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-02-04 EP disclosed
US-5708132-A Method for the production of nitrile rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-01-13 US disclosed
CN-1159814-A Thermosetting elastomer DOW CHEMICAL CO (US) 1997-09-17 CN disclosed
EP-0778852-A1 THERMOSET ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1997-06-18 EP disclosed
WO-1996007681-A1 THERMOSET ELASTOMERS THE DOW CHEMICAL COMPANY (US) 1996-03-14 WO disclosed
US-4711735-A Coolant additive with corrosion inhibitive and scale preventative properties GULLEY HAROLD J (US) 1987-12-08 US disclosed