2-Mercaptobenzothiazole

2-Mercaptobenzothiazole

SCHEMBL78798

Sc1nc2ccccc2s1.[Zn]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
HPGD P15428 2/20 0.52
ADRA2A P08913 1/20 0.52
FBP1 P09467 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
DRD2 P14416 1/20 0.52
ALOX15 P16050 1/20 0.52
ADRA2B P18089 1/20 0.52
ADRA2C P18825 1/20 0.52
DRD1 P21728 1/20 0.52
MC5R P33032 1/20 0.52
OPRM1 P35372 1/20 0.52
DRD3 P35462 1/20 0.52
OPRK1 P41145 1/20 0.52
CCR2 P41597 1/20 0.52
HTR6 P50406 1/20 0.52
SLC6A3 Q01959 1/20 0.52
PDK1 Q15118 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzothiazole SCHEMBL7640197 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL17684719 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL15823708 0.98 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL3789760 0.98 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL23237 0.98 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL29509878 0.98 ALDH1A1 (0.54) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL10429471 0.95 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL8158663 0.95 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL20537310 0.95 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A
2-Mercaptobenzothiazole SCHEMBL11575316 0.95 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1HPGDADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3726 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136116-B Preparation method and application of mesoporous silica 江山市华顺有机硅有限公司 2026-05-15 CN claimed
EP-4719411-A2 QUINOLINEAMINE AND PYRIDOQUINOLINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF Flexsys IP Holdings, LLC (US) 2026-04-08 EP claimed
EP-4704835-A2 ANTIDEGRADANT BIS(DIHYDRO AND TETRAHYDROQUINOLINE) COMPOUNDS AND USES THEREOF Flexsys IP Holdings, LLC (US) 2026-03-11 EP claimed
EP-4687881-A2 HETEROARYL ANTIDEGRADANTS Flexsys IP Holdings, LLC (US) 2026-02-11 EP claimed
EP-4687882-A2 6-AMINOQUINOLINE ANTIDEGRADANTS Flexsys IP Holdings, LLC (US) 2026-02-11 EP claimed
EP-4676471-A2 QUINOLINEIMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF Flexsys IP Holdings, LLC (US) 2026-01-14 EP claimed
EP-4634284-A1 VULCANIZING AGENT FOR BITUMEN TotalEnergies OneTech (FR) 2025-10-22 EP claimed
WO-2025137303-A1 META-PHENYLENEDIAMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA L.P. (US) 2025-06-26 WO claimed
US-20250171623-A1 Softer Blended Nitrile Elastomeric Article BANK OF AMERICA, N.A., AS LEAD COLLATERAL AGENT 2025-05-29 US claimed
EP-4558138-A2 AMINOINDOLE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA L.P. (US) 2025-05-28 EP claimed
EP-0165207-A1 Powder paintings for flatted coatings CIBA-GEIGY AG (CH) 1985-12-18 EP claimed
US-4548689-A RADICAL POLYMERIZABLE MONOMER, KETOCARBONYL COMPOUND AND MERCAPTOB MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-10-22 US claimed
EP-0136186-A2 Photocurable resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP claimed
EP-0129069-A2 Process for bonding non-polar or highly crystalline resin substrats to each other or to another material TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1984-12-27 EP claimed
US-4461875-A ETHYLENE-PROPYLENE-NON-CONJUGATED DIENE TERPOLYMER AND/OR BUTYL RUBBER WITH THIURAM HEXASULFIDE, AND SULFUR COMPOUND UNIROYAL, INC. (US) 1984-07-24 US claimed
EP-0062989-A2 Latex foam rubbers DUNLOP LIMITED (GB) 1982-10-20 EP claimed
US-4248985-A Sulfur-curable acrylic rubber composition NIPPON ZEON CO., LTD. (JP) 1981-02-03 US claimed
US-4065362-A Purification of organic isocyanates SUMITOMO BAYER URETHANE CO., LTD. (JA) 1977-12-27 US claimed
US-4017458-A ZINC 2-MERCAPTOBENZOTHIAZOLE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-04-12 US claimed
US-4003843-A SILANE, THIAZOLE, GUANIDINE, THIURAM BAYER AKTIENGESELLSCHAFT (DT) 1977-01-18 US claimed