Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 5/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 2/20 | 0.52 |
| ▸ | CCND1 | P24385 | 2/20 | 0.52 |
| ▸ | TNKS | O95271 | 5/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779739 | 0.79 | ABCG2 (0.49) | NPC1RAB9AMAPK1KDM4EMAPT | |
| SCHEMBL8779566 | 0.78 | ABCG2 (0.48) | CYP1A2NPC1RAB9AMAPK1KDM4E | |
| SCHEMBL3786521 | 0.78 | ABCG2 (0.47) | NPC1RAB9AMAPK1KDM4EMAPT | |
| SCHEMBL30691836 | 0.75 | PDGFRB (0.50) | NPC1RAB9AMAPK1KDM4EMAPT | |
| SCHEMBL16007517 | 0.74 | GUSB (1.00) | GUSBCYP1A1CYP1B1CYP1A2CDK4 | |
| SCHEMBL31238611 | 0.74 | GUSB (1.00) | GUSBCYP1A1CYP1B1CYP1A2CDK4 | |
| SCHEMBL6122044 | 0.73 | TNKS2 (0.56) | GUSBCYP1A1CYP1B1TNKSTNKS2 | |
| SCHEMBL3785974 | 0.73 | ALDH1A1 (0.46) | CYP1A2NPC1RAB9AMAPK1KDM4E | |
| SCHEMBL29360950 | 0.73 | ALDH1A1 (0.46) | CYP1A2NPC1RAB9AMAPK1KDM4E | |
| SCHEMBL15690958 | 0.72 | GUSB (1.00) | GUSBCYP1A1CYP1B1CYP1A2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | GUSB 628/4885CYP1A1 4/4885CYP1B1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.