Sugi Predict

Sugi Predict / Compounds / SCHEMBL3785974

SCHEMBL3785974

SCHEMBL3785974

COc1ccc(-c2nc(-c3ncc4ccccc4n3)ccc2C)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.46
▸ KDM4E B2RXH2 5/20 0.46
▸ MAPK1 P28482 2/20 0.46
▸ PDE10A Q9Y233 1/20 0.44
▸ PDGFRB P09619 1/20 0.43
▸ PDGFRA P16234 1/20 0.43
▸ NPC1 O15118 5/20 0.43
▸ RAB9A P51151 5/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ L3MBTL1 Q9Y468 4/20 0.42
▸ MAPT P10636 2/20 0.42
▸ ABCG2 Q9UNQ0 2/20 0.42
▸ NFKB1 P19838 1/20 0.41
▸ NFKB2 Q00653 1/20 0.41
▸ RELA Q04206 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ GLA P06280 1/20 0.39
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360950 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMAPK1PDE10APDGFRB
SCHEMBL28975826 0.93 ALDH1A1 (0.41) ALDH1A1KDM4EMAPK1PDE10APDGFRB
SCHEMBL8776495 0.90 SMN1; SMN2 (0.54) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL8777021 0.90 NPC1 (0.45) ALDH1A1KDM4EPDE10APDGFRBPDGFRA
SCHEMBL8776620 0.89 CYP1A2 (0.39) ALDH1A1KDM4EMAPK1PDE10ANPC1
SCHEMBL8777022 0.89 CYP1A2 (0.46) PDE10ANPC1RAB9ASMN1; SMN2MAPT
SCHEMBL3789618 0.88 CYP1A2 (0.45) ALDH1A1KDM4EMAPK1PDE10APDGFRB
SCHEMBL30129477 0.88 CYP1A2 (0.45) ALDH1A1KDM4EMAPK1PDE10APDGFRB
SCHEMBL8777037 0.87 ADORA2A (0.43) ALDH1A1KDM4EPDGFRBPDGFRANPC1
SCHEMBL3785988 0.85 CYP1A2 (0.45) PDE10ANPC1RAB9ACYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 — — EP claimed
WO-2025223904-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-30 — — WO claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 — — EP claimed
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 — — EP claimed
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2024-11-07 — — US claimed
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4384016-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2024-06-19 — — EP claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 — — CN claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 — — WO claimed
WO-2024104813-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 — — WO claimed
EP-3057424-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND Bayer CropScience Aktiengesellschaft (DE) 2016-08-24 — — EP claimed
EP-3011832-A1 FUNGICIDAL COMBINATION COMPRISING PHENOXYPHENYLAMIDINES AND FURTHER FUNGICIDE Bayer CropScience AG (DE) 2016-04-27 — — EP claimed
EP-2922400-A1 ACTIVE COMPOUND COMBINATIONS Bayer CropScience AG (DE) 2015-09-30 — — EP claimed
WO-2015055707-A9 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND BAYER CROPSCIENCE AG (DE) 2015-07-02 — — WO claimed
WO-2015055707-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND A FUNGICIDAL COMPOUND BAYER CROPSCIENCE AG (DE) 2015-04-23 — — WO claimed
WO-2014079789-A1 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-05-30 — — WO claimed
EP-2735231-A1 Active compound combinations Bayer CropScience AG (DE) 2014-05-28 — — EP claimed
WO-2012069652-A2 FUNGICIDE MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-05-31 — — WO claimed
US-20120129875-A1 SUBSTITUTED QUINAZOLINES AS FUNGICIDES SYNGENTA CROP PROTECTION, LLC (US) 2012-05-24 — — US claimed
WO-2010136475-A1 SUBSTITUTED QUINAZOLINES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-12-02 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 ALDH1A1 63/4885KDM4E 3353/4885MAPK1 1033/4885
US-20120129875-A1 SUBSTITUTED QUINAZOLINES AS FUNGICIDES NAT1, NQO2, NOX1 ALDH1A1 1125/4885KDM4E 1794/4885MAPK1 158/4885
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE DDT, TH, HPD ALDH1A1 517/4885KDM4E 249/4885MAPK1 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.