Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790927 | 1.00 | AOC3 (0.62) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL474635 | 0.79 | AOC3 (0.60) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL474636 | 0.79 | AOC3 (0.60) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL16735533 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL16735541 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL2189412 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL2189408 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL2212219 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL2212215 | 0.77 | AOC3 (1.00) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL3791186 | 0.75 | ALDH1A1 (0.40) | AOC3ALDH1A1KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010125469-A1 | PYRIMIDINEDIONE-FUSED HETEROCYCLIC COMPOUNDS AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-11-04 | — | — | WO | disclosed |