SCHEMBL379118

SCHEMBL379118

CCCCC(CC)COC(=O)c1ccccc1N

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.82
CYP3A4 P08684 5/20 0.82
CA2 P00918 1/20 0.82
LMNA P02545 4/20 0.74
PRSS1 P07477 1/20 0.73
PRSS2 P07478 1/20 0.73
PRSS3 P35030 1/20 0.73
HSD17B10 Q99714 7/20 0.63
TSHR P16473 9/20 0.61
MAPK1 P28482 4/20 0.61
KDM4E B2RXH2 1/20 0.60
POLB P06746 1/20 0.60
TDP1 Q9NUW8 3/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
TP53 P04637 2/20 0.47
CFTR P13569 1/20 0.46
NPC1 O15118 1/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(2-Ethylhexyl)Phthalate SCHEMBL21733281 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl)Phthalate SCHEMBL29411299 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL20271 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL2864306 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL29351619 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4CA2LMNAPRSS1
SCHEMBL11274168 0.90 ALDH1A1 (0.73) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL4602015 0.89 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL74067 0.89 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL22190333 0.89 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2LMNAPRSS1
Bis(2-Ethylhexyl) Phthalate SCHEMBL5842020 0.89 ALDH1A1 (0.97) ALDH1A1CYP3A4CA2LMNAPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
JP-10158140-A None JP disclosed
WO-2024046955-A1 IMPROVED PROCESS FOR PREPARING P-AMINOBENZOIC ACID-2-ETHYLHEXYL ESTER BASF SE (DE) 2024-03-07 WO disclosed
EP-4245293-A1 USE OF SUGAR AMINES AS COMPLEXING AGENTS Clariant International Ltd (CH) 2023-09-20 EP disclosed
WO-2023100810-A1 METHOD FOR TREATING KERATIN SUBSTANCE OR FIBER FOR HEAD DECORATION PRODUCTS 花王株式会社 2023-06-08 WO disclosed
EP-3080169-B1 METHOD FOR PREPARING FUNCTIONALIZED GRAFT POLYMERS LUBRIZOL CORP (US) 2022-08-17 EP disclosed
CN-109415553-B Plasticized thermoset resins and related cured resins, curing methods, and articles comprising cured resins 马萨诸塞大学 2022-08-05 CN disclosed
CN-109843941-A Polymer network structure is controlled by nanogel 科罗拉多大学董事会,法人团体 2019-06-04 CN disclosed
US-9708422-B2 Method for preparing functionalized graft polymers THE LUBRIZOL CORPORATION (US) 2017-07-18 US disclosed
EP-2408884-B1 ANTHRANILIC ESTERS AS ADDITIVES IN LUBRICANTS LUBRIZOL CORP (US) 2016-11-16 EP disclosed
US-6037487-A UNSATURATED AMINE AND CARBONYL-CONTAINING COMPOUNDS OF GIVEN FORMULA WITH HIGH ABSORPTION IN THE UV-A RANGE BASF AKTIENGESELLSCHAFT (DE) 2000-03-14 US disclosed
CN-1229353-A Photoprotective compositions PROCTER & GAMBLE (US) 1999-09-22 CN disclosed
US-5945091-A Photo-stable cosmetic and pharmaceutical formulations containing UV-filters BASF AKTIENGESELLSCHAFT (DE) 1999-08-31 US disclosed
EP-0852137-A2 Cosmetic compositions containing a photostable UV-A filter BASF AKTIENGESELLSCHAFT (DE) 1998-07-08 EP disclosed
JP-H10158140-A COSMETIC AND PHARMACEUTICAL PREPARATION CONTAINING UV-FILTER HAVING LIGHT STABILITY BASF AG 1998-06-16 JP disclosed
CN-1118987-A Cosmetic compositions containing surface treated pigments PROCTER & GAMBLE (US) 1996-03-20 CN disclosed
EP-0091019-B1 DISAZO DYESTUFFS BASF Aktiengesellschaft (DE) 1985-07-17 EP disclosed
US-4521216-A USED FOR PETROLEUM, SOLVENTS AND FUEL ADDITIVES BASF AKTIENGESELLSCHAFT (DE) 1985-06-04 US disclosed
EP-0091019-A1 Disazo dyestuffs BASF Aktiengesellschaft (DE) 1983-10-12 EP disclosed
US-4021470-A LUBRICANT STABILIZERS MOBIL OIL CORPORATION (US) 1977-05-03 US disclosed