SCHEMBL379162

SCHEMBL379162

O=CCCC1=CCC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21335139 0.88 HIF1A (0.33)
SCHEMBL14399757 0.82
SCHEMBL7494175 0.73
SCHEMBL28138014 0.72
SCHEMBL3227379 0.71
SCHEMBL371505 0.71
SCHEMBL17611074 0.70
SCHEMBL17611180 0.68 MAOA (0.35)
SCHEMBL379058 0.68
SCHEMBL3973741 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2805765-B1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF Ru (II) CATALYSTS JOHNSON MATTHEY PLC (GB) 2020-12-23 EP disclosed
CN-106466641-B Process for hydrogenating ketones in the presence of Ru (II) catalysts 约翰森·马瑟公开有限公司 2020-06-09 CN disclosed
US-10406514-B2 Process for hydrogenating ketones in the presence of Ru(II) catalysts JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-09-10 US disclosed
US-20180290133-A1 Process For Hydrogenating Ketones In The Presence Of RU(II) Catalysts JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2018-10-11 US disclosed
EP-2408557-B1 Process for making Ru (II) catalysts JOHNSON MATTHEY PLC (GB) 2017-03-15 EP disclosed
EP-2408557-B1 Process for making Ru (II) catalysts JOHNSON MATTHEY PLC (GB) 2017-03-15 EP disclosed
US-20160271599-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PLC (GB) 2016-09-22 US disclosed
US-20160271599-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PLC (GB) 2016-09-22 US disclosed
US-20160271599-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PLC (GB) 2016-09-22 US disclosed
US-9416100-B2 Process for hydrogenating ketones in the presence of Ru(II) catalysts JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2016-08-16 US disclosed
US-20140357903-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-12-04 US disclosed
US-20140357903-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-12-04 US disclosed
EP-2805765-A1 Process for hydrogenating ketones in the presence of RU (II) catalysts Johnson Matthey Public Limited Company (GB) 2014-11-26 EP disclosed
EP-2805765-A1 Process for hydrogenating ketones in the presence of RU (II) catalysts Johnson Matthey Public Limited Company (GB) 2014-11-26 EP disclosed
US-20120123142-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-17 US disclosed
US-20120123142-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-17 US disclosed
US-20120123142-A1 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU(II) CATALYSTS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-17 US disclosed
EP-2408557-A2 PROCESS FOR HYDROGENATING KETONES IN THE PRESENCE OF RU (II) CATALYSTS Johnson Matthey Public Limited Company (GB) 2012-01-25 EP disclosed
WO-2010106364-A2 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-09-23 WO disclosed
WO-2010106364-A2 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-09-23 WO disclosed