Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17237128 | 0.81 | EPHX2 (0.49) | EPHX2TRPV1NPC1RAB9AFAAH | |
| SCHEMBL10923878 | 0.78 | PARP10 (0.53) | ALDH1A1MAPTMEN1TSHRKMT2A | |
| SCHEMBL4475347 | 0.78 | NPC1 (0.60) | MAPTEPHX2TRPV1NPC1RAB9A | |
| SCHEMBL20015846 | 0.78 | EPHX2 (0.57) | MAPTTP53SMN1; SMN2EPHX2RAPGEF3 | |
| SCHEMBL23389922 | 0.78 | MAPT (0.49) | ALDH1A1MAPTTDP1MEN1TP53 | |
| SCHEMBL17338824 | 0.77 | EPHX2 (0.51) | ALDH1A1MAPTEPHX2TRPV1NPC1 | |
| SCHEMBL136576 | 0.77 | MMP2 (0.47) | ALDH1A1MAPTTDP1MEN1TP53 | |
| SCHEMBL10719753 | 0.77 | GSK3B (0.43) | ALDH1A1MAPTTDP1MEN1TP53 | |
| SCHEMBL7714214 | 0.76 | EPHX2 (0.55) | MAPTMEN1TP53KMT2ASMN1; SMN2 | |
| SCHEMBL219654 | 0.76 | EPHX2 (0.68) | ALDH1A1TP53TSHRHSD17B10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190050533-A1 | Redox-related context adjustments to a reference bioprocess model used in learning systems and methods based on redox indicators | PTC THERAPEUTICS, INC. | 2019-02-14 | — | — | US | disclosed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9630933-B2 | Method for producing 1-H-tetrazole derivative | NIPPON SODA CO., LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | NIPPON SODA CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| EP-2408434-A1 | TREATING ALZHEIMER'S DISEASE AND OSTEOPOROSIS AND REDUCING AGING | IPINTL, LLC (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107702-A1 | TREATING ALZHEIMER'S DISEASE AND OSTEOPOROSIS AND REDUCING AGING | IPINTL, LLC (US) | 2010-09-23 | — | — | WO | disclosed |
| US-6291203-B1 | UNSYMMETRICAL FLUORESCENT DYES FOR ORGANELLES | MOLECULAR PROBES, INC. | 2001-09-18 | — | — | US | disclosed |
| EP-0093338-A1 | Method for the preparation of cyanohydrine-carboxylic-acid esters | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322021-A1 | METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | CBR1, RIF1, CBR3 | ALDH1A1 768/4885MAPT 4665/4885TDP1 4383/4885 |
| US-20150158829-A1 | METHOD FOR PRODUCING AZIDE COMPOUND, AND METHOD FOR PRODUCING 1-H-TETRAZOLE DERIVATIVE | AS3MT, MSMO1, ABL1 | ALDH1A1 645/4885MAPT 4506/4885TDP1 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.