Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098927 | 0.86 | — | — | |
| SCHEMBL3383963 | 0.78 | TSHR (0.43) | LMNANFKB1CYP1A2SLC22A6GABRP | |
| SCHEMBL2235480 | 0.76 | LMNA (0.48) | LMNACYP2D6MAPTNFKB1CYP1A2 | |
| SCHEMBL7738368 | 0.76 | LMNA (0.48) | LMNACYP2D6MAPTNFKB1CYP1A2 | |
| SCHEMBL8577520 | 0.75 | LMNA (0.48) | LMNANFKB1CYP1A2HSD17B10SLC22A6 | |
| SCHEMBL1712974 | 0.74 | LMNA (0.47) | LMNACYP2D6MAPTNFKB1CYP1A2 | |
| SCHEMBL125280 | 0.74 | — | — | |
| SCHEMBL13658757 | 0.74 | LMNA (0.53) | LMNANFKB1CYP1A2HSD17B10SLC22A6 | |
| SCHEMBL14360701 | 0.74 | LMNA (0.53) | LMNAMAPTNFKB1CYP1A2SLC22A6 | |
| SCHEMBL29660871 | 0.74 | LMNA (0.53) | LMNANFKB1CYP1A2SLC22A6GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2015-05-14 | — | — | US | disclosed |
| WO-2014070092-A1 | FUNCTIONALIZED CELLULOSE NANOCRYSTALS, A METHOD FOR THE PREPARATION THEREOF AND USE OF FUNCTIONALIZED CELLULOSE NANOCRYSTALS IN COMPOSITES AND FOR GRAFTING | SWETREE TECHNOLOGIES AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
| EP-2408779-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | Photobiotics Limited (GB) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010106341-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
| US-5466710-A | Heterobicycloalkanes as pesticidal compounds | ROUSSEL UCLAF (FR) | 1995-11-14 | — | — | US | disclosed |
| US-5116862-A | Acetylenic trithiabicyclo(2.2.2)octanes | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-05-26 | — | — | US | disclosed |
| EP-0300797-A1 | Pesticidal compounds | ROUSSEL UCLAF (FR) | 1989-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | LMNA 1929/4885CYP2D6 489/4885MAPT 2363/4885 |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | LMNA 1940/4885CYP2D6 391/4885MAPT 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.