Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044982 | 0.86 | RAB9A (0.68) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3049281 | 0.83 | LMNA (0.77) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL31504583 | 0.82 | RAB9A (0.64) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL21589413 | 0.82 | NPC1 (0.65) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL27004512 | 0.82 | RAB9A (0.64) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL4921505 | 0.81 | NPC1 (0.62) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL14808362 | 0.81 | RAB9A (0.65) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL24071962 | 0.79 | RAB9A (0.88) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944350 | 0.79 | RAB9A (0.88) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30944411 | 0.79 | RAB9A (0.88) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103381-A1 | SPIROCYCLIC PIPERIDINE DERIVATIVES AS TRPM 8 MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-09-16 | — | — | WO | disclosed |