Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | PTPRB | P23467 | 10/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455223 | 0.83 | PTPRB (0.48) | CA1CA2PTPRBPTPN2PTPN1 | |
| SCHEMBL4639713 | 0.81 | CA1 (0.66) | CA1CA2KDM1AMEN1KMT2A | |
| SCHEMBL6696494 | 0.78 | KEAP1 (0.56) | CA1CA2HPGDCA12CA9 | |
| SCHEMBL3059775 | 0.75 | HPGD (0.60) | CA1CA2HPGDKMT2A | |
| SCHEMBL4591628 | 0.75 | CA1 (0.64) | CA1CA2PTPRBHPGDMEN1 | |
| SCHEMBL10587934 | 0.74 | PTPN1 (0.59) | CA1CA2PTPN1 | |
| SCHEMBL3088460 | 0.73 | CA1 (0.61) | CA1CA2MEN1KMT2ACA12 | |
| SCHEMBL7863309 | 0.73 | PTPRB (0.42) | CA1CA2PTPRBPTPN2PTPN1 | |
| SCHEMBL1230858 | 0.73 | KEAP1 (0.53) | CA1CA2PTPRBPTPN2PTPN1 | |
| SCHEMBL3041175 | 0.73 | CA1 (0.52) | CA1CA2PTPRBPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127381-A1 | DIAGNOSIS, MONITORING, PROGNOSIS, PREVENTION AND TREATMENT OF ANEURYSMS | JAMES COOK UNIVERSITY (AU) | 2010-11-11 | — | — | WO | disclosed |
| US-7427496-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-09-23 | — | — | US | disclosed |
| US-20060183772-A1 | To inhibit tumor growth in an animal; to induce apoptosis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-17 | — | — | US | disclosed |