Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12054668 | 0.83 | KEAP1 (0.75) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL478987 | 0.81 | KEAP1 (0.54) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL15904063 | 0.81 | KEAP1 (0.54) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL4959361 | 0.81 | CA1 (0.66) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL3059775 | 0.79 | HPGD (0.60) | SMN1; SMN2LMNAHPGDHTTCA1 | |
| SCHEMBL10193562 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL9835622 | 0.78 | KEAP1 (0.56) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL3793259 | 0.78 | CA1 (0.42) | HPGDCA12CA1CA2CA9 | |
| SCHEMBL3099756 | 0.78 | HPGD (0.53) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL31041151 | 0.77 | KIF11 (0.79) | KEAP1SMN1; SMN2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | disclosed |
| EP-0558076-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5891614-A | FORMING HALOGEN COMPOSITION GAP FACES AT TIME OF NUCLEATION TO PRODUCE TABULAR GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| WO-1998037078-A1 | SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED THIOPHENES AND OF ARRAYS OF SUBSTITUTED THIOPHENES | NOVO NORDISK A/S (DK) | 1998-08-27 | — | — | WO | disclosed |
| EP-0528435-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5582962-A | COLLOID LAYERS COMPRISING A DISPERSE DYE PARTICLES | KONICA CORPORATION (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0401709-B1 | X-ray photographic material | FUJI PHOTO FILM CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0679935-A2 | Silver halide photographic light-sensitive material and the processing method thereof | KONICA CORPORATION (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5340707-A | Containing specified pyrazolone dye; storage stability | KONICA CORPORATION (JP) | 1994-08-23 | — | — | US | disclosed |
| US-5328818-A | Support with color couplers in emulsions in multilayer element | FUJI PHOTO FILM CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| US-5147769-A | Image sharpness | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0215124-B1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| EP-0435561-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1991-07-03 | — | — | EP | disclosed |
| EP-0434413-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0401709-A2 | X-ray photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4925782-A | Silver halide photographic light-sensitive element containing water soluble dye compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4879204-A | HIGH CONTRAST | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4764455-A | Color image-forming process | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0215124-A1 | SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
| US-3931142-A | Heterocyclic containing disazo compounds | CIBA-GEIGY AG (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | KEAP1 1957/4885SMN1; SMN2 3350/4885ALDH1A1 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.