Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 9/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691038 | 0.92 | PTK6 (0.35) | PTK6LCKAURKBP2RX7MARK3 | |
| SCHEMBL3797185 | 0.90 | PTK6 (0.37) | PTK6LCKAURKBTRPV1 | |
| SCHEMBL13228712 | 0.88 | P2RX7 (0.36) | P2RX7TRPV1 | |
| SCHEMBL3791562 | 0.87 | P2RX7 (0.34) | P2RX7TRPV1 | |
| SCHEMBL3684454 | 0.85 | P2RX7 (0.35) | P2RX7TRPV1 | |
| SCHEMBL3687819 | 0.84 | AURKB (0.34) | PTK6LCKAURKBP2RX7MARK3 | |
| SCHEMBL3689868 | 0.83 | MARK3 (0.34) | PTK6LCKAURKBP2RX7MARK3 | |
| SCHEMBL3784636 | 0.83 | PTK6 (0.37) | PTK6LCKAURKB | |
| SCHEMBL3709613 | 0.82 | PTK6 (0.35) | PTK6LCKAURKBTRPV1 | |
| SCHEMBL13229133 | 0.82 | MARK3 (0.34) | PTK6LCKAURKBP2RX7MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204265-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections | GENELABS TECHNOLOGIES, INC. | 2010-08-12 | — | — | US | claimed |
| US-20100204265-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections | GENELABS TECHNOLOGIES, INC. | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204265-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections | OAT, HAVCR2, CPS1 | PTK6 4396/4885LCK 2497/4885AURKB 1908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.