SCHEMBL379350

SCHEMBL379350

O=C(O)CCC(C(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.44
HIF1A Q16665 1/20 0.44
CYP1A2 P05177 2/20 0.43
KEAP1 Q14145 1/20 0.43
OPRM1 P35372 4/20 0.43
DRD3 P35462 2/20 0.43
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
ALDH1A1 P00352 4/20 0.43
ESR1 P03372 1/20 0.43
CYP3A4 P08684 1/20 0.43
ESR2 Q92731 1/20 0.43
NR4A2 P43354 1/20 0.42
AKR1B1 P15121 1/20 0.41
FFAR1 O14842 2/20 0.41
HDAC3 O15379 1/20 0.41
MAPK1 P28482 1/20 0.41
ADRA1A P35348 1/20 0.41
HDAC4 P56524 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523363 0.88 HDAC3 (0.47) CYP2C19HIF1ACYP1A2KEAP1OPRM1
SCHEMBL20564637 0.86 HDAC3 (0.47) CYP2C19HIF1ACYP1A2KEAP1OPRM1
SCHEMBL3175352 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL7006072 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL3165603 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL7011842 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL7006022 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL20564310 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL10793796 0.85 HDAC3 (0.50) CYP2C19HIF1AOPRM1DRD3DRD2
SCHEMBL9562152 0.84 ESR1 (0.62) HIF1AALDH1A1ESR1CYP3A4ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111378123-A Polyamide resin and preparation method thereof 江苏瑞美福新材料有限公司 2020-07-07 CN claimed
CN-101930189-B Purified polyester resins for toner performance improvement XEROX CORP 2014-07-23 CN claimed
US-8168361-B2 Curable toner compositions and processes XEROX CORPORATION (US) 2012-05-01 US claimed
US-20110091803-A1 CURABLE TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2011-04-21 US claimed
US-7910276-B2 Toner compositions XEROX CORPORATION (US) 2011-03-22 US claimed
CN-101930189-A Can improve the purified polyester resins of toner performance XEROX CORP 2010-12-29 CN claimed
US-7785763-B2 Emulsion aggregation processes XEROX CORPORATION (US) 2010-08-31 US claimed
US-7736831-B2 Emulsion/aggregation process using coalescent aid agents XEROX CORPORATION (US) 2010-06-15 US claimed
EP-1850187-B1 Toner Compostions and Processes XEROX CORP (US) 2009-08-19 EP claimed
US-7553595-B2 Toner compositions and processes XEROX CORPORATION (US) 2009-06-30 US claimed
US-20080199797-A1 photocurable unsaturated polymeric resin, selected from amorphous/crystalline or both ( propoxylated bisphenol A fumarate, copoly(ethylene-dodecanoate)-copoly-(ethylene-fumarate) , photoinitiator (phenylbis(2,4,6-trimethylvbenzyoyl) phosphine oxide) for initiating crosslinking of unsaturated polyester XEROX CORPORATION (US) 2008-08-21 US claimed
US-20080113291-A1 EMULSION AGGREGATION TONER, DEVELOPER, AND METHOD OF MAKING THE SAME XEROX CORPORATION (US) 2008-05-15 US claimed
US-20080090163-A1 Emulsion aggregation processes XEROX CORPORATION (US) 2008-04-17 US claimed
US-20080063965-A1 Emulsion/aggregation processes using coalescent aid agents XEROX CORPORATION (US) 2008-03-13 US claimed
US-20070254228-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2007-11-01 US claimed
EP-1850187-A1 Toner Compostions and Processes Xerox Corporation (US) 2007-10-31 EP claimed
US-20070141495-A1 Emulsion/aggregation toners having novel dye complexes XEROX CORPORATION (US) 2007-06-21 US claimed
US-20070020542-A1 Emulsion aggregation, developer, and method of making the same XEROX CORPORATION (US) 2007-01-25 US claimed
US-4208464-A POLYESTERIMIDES NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1980-06-17 US claimed
US-4101488-A POLYESTERIMIDE RESIN NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1978-07-18 US claimed