Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221554 | 0.89 | ESR1 (0.54) | ESR1ESR2CYP3A4ALDH1A1CA2 | |
| SCHEMBL4212101 | 0.86 | ESR1 (0.51) | ESR1ESR2CYP3A4ALDH1A1CA2 | |
| SCHEMBL4214690 | 0.86 | ESR1 (0.51) | ESR1ESR2CYP3A4ALDH1A1CA2 | |
| SCHEMBL379350 | 0.84 | CYP2C19 (0.44) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL4016674 | 0.83 | CHEK1 (0.44) | ESR1ESR2CYP3A4ALDH1A1CHEK1 | |
| SCHEMBL1253192 | 0.83 | ALDH1A1 (0.47) | ESR1ESR2CYP3A4ALDH1A1CHEK1 | |
| SCHEMBL2220443 | 0.81 | ESR1 (0.44) | ESR1ESR2CYP3A4ALDH1A1CA2 | |
| SCHEMBL890797 | 0.81 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1CA2 | |
| SCHEMBL1916607 | 0.80 | ALDH1A1 (0.41) | ESR1ESR2CYP3A4ALDH1A1CHEK1 | |
| SCHEMBL4214180 | 0.80 | CA2 (0.48) | ESR1ESR2CYP3A4ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200385-A | Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness | RICOH COMPANY, LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5126486-A | Color developers for leuco dyes in thermal printing | RICOH COMPANY, LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| US-4978651-A | With a colorless or light colored leuco dye for inducing color formation | RICOH COMPANY, LTD. (JP) | 1990-12-18 | — | — | US | disclosed |