Glutarate

Glutarate

SCHEMBL379351

O=C(O)CCCC(=O)O.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC7 Q8WUI4 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC10 Q969S8 2/20 0.58
HDAC11 Q96DB2 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
HDAC9 Q9UKV0 2/20 0.58
HDAC5 Q9UQL6 2/20 0.58
MAPK1 P28482 1/20 0.58
ADRA1A P35348 1/20 0.58
SLC6A3 Q01959 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
GLA P06280 1/20 0.55
CA3 P07451 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL28110215 1.00 HDAC3 (0.58) HDAC3HDAC4HDAC1HDAC7HDAC2
Adipic Acid SCHEMBL523364 0.95 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
Phenol SCHEMBL4623314 0.93 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Azelaic Acid SCHEMBL28109737 0.93 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Sebacic Acid SCHEMBL28538398 0.93 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Succinic Acid SCHEMBL6388337 0.90 CA2 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Succinic Acid SCHEMBL374785 0.90 CA2 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
Valeric Acid SCHEMBL22972918 0.87 HSD17B3 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
Valeric Acid SCHEMBL5691417 0.87 HSD17B3 (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
Glutarate SCHEMBL28917233 0.86 HDAC3 (0.46) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101930189-B Purified polyester resins for toner performance improvement XEROX CORP 2014-07-23 CN claimed
US-8168361-B2 Curable toner compositions and processes XEROX CORPORATION (US) 2012-05-01 US claimed
US-20110091803-A1 CURABLE TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2011-04-21 US claimed
US-7910276-B2 Toner compositions XEROX CORPORATION (US) 2011-03-22 US claimed
CN-101930189-A Can improve the purified polyester resins of toner performance XEROX CORP 2010-12-29 CN claimed
US-7785763-B2 Emulsion aggregation processes XEROX CORPORATION (US) 2010-08-31 US claimed
US-7736831-B2 Emulsion/aggregation process using coalescent aid agents XEROX CORPORATION (US) 2010-06-15 US claimed
EP-1850187-B1 Toner Compostions and Processes XEROX CORP (US) 2009-08-19 EP claimed
US-7553595-B2 Toner compositions and processes XEROX CORPORATION (US) 2009-06-30 US claimed
US-7498112-B2 Emulsion/aggregation toners having novel dye complexes XEROX CORPORATION (US) 2009-03-03 US claimed
US-7429443-B2 Method of making emulsion aggregation toner XEROX CORPORATION (US) 2008-09-30 US claimed
US-20080210124-A1 CORE-SHELL POLYMER PARTICLES XEROX CORPORATION (US) 2008-09-04 US claimed
US-20080199797-A1 photocurable unsaturated polymeric resin, selected from amorphous/crystalline or both ( propoxylated bisphenol A fumarate, copoly(ethylene-dodecanoate)-copoly-(ethylene-fumarate) , photoinitiator (phenylbis(2,4,6-trimethylvbenzyoyl) phosphine oxide) for initiating crosslinking of unsaturated polyester XEROX CORPORATION (US) 2008-08-21 US claimed
US-20080113291-A1 EMULSION AGGREGATION TONER, DEVELOPER, AND METHOD OF MAKING THE SAME XEROX CORPORATION (US) 2008-05-15 US claimed
US-20080090163-A1 Emulsion aggregation processes XEROX CORPORATION (US) 2008-04-17 US claimed
US-20080063965-A1 Emulsion/aggregation processes using coalescent aid agents XEROX CORPORATION (US) 2008-03-13 US claimed
US-20070254228-A1 TONER COMPOSITIONS AND PROCESSES XEROX CORPORATION (US) 2007-11-01 US claimed
EP-1850187-A1 Toner Compostions and Processes Xerox Corporation (US) 2007-10-31 EP claimed
US-20070141495-A1 Emulsion/aggregation toners having novel dye complexes XEROX CORPORATION (US) 2007-06-21 US claimed
US-20070020542-A1 Emulsion aggregation, developer, and method of making the same XEROX CORPORATION (US) 2007-01-25 US claimed