SCHEMBL379353

SCHEMBL379353

CCN(CC)CCCC[Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HRH4 Q9H3N8 2/20 0.33
HRH3 Q9Y5N1 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
CHRM2 P08172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379299 0.93 ALDH1A1 (0.33) ALDH1A1HRH4HRH3SIGMAR1
SCHEMBL16813541 0.89 ALDH1A1 (0.32) ALDH1A1
SCHEMBL16390223 0.89 CHRM2 (0.32) ALDH1A1CHRM2
SCHEMBL16813822 0.85 ALDH1A1 (0.32) ALDH1A1
SCHEMBL15611859 0.84 BCHE (0.35) ALDH1A1
SCHEMBL379785 0.84 MEN1 (0.31)
SCHEMBL31687742 0.83 ALDH1A1 (0.31) ALDH1A1
SCHEMBL31687753 0.83 ALDH1A1 (0.31) ALDH1A1
SCHEMBL2244060 0.81
SCHEMBL18186131 0.81 DNM1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511334-B1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2018-04-25 EP disclosed
EP-2174801-B1 Rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2016-10-19 EP disclosed
US-8800621-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-12 US disclosed
CN-101747538-B Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER IND 2013-05-01 CN disclosed
CN-101735498-B Rubber composition and tire SUMITOMO RUBBER IND 2013-03-13 CN disclosed
US-20120283354-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-08 US disclosed
EP-2366558-B1 Tire rubber composition and heavy-load tire SUMITOMO RUBBER IND (JP) 2012-10-31 EP disclosed
EP-2511334-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2012-10-17 EP disclosed
EP-2366557-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-05-23 EP disclosed
US-8163821-B2 Tire rubber composition and heavy-load tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-24 US disclosed
EP-2366557-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
CN-101747538-A Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER IND 2010-06-23 CN disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
CN-101735498-A Rubber composition and tire SUMITOMO RUBBER IND 2010-06-16 CN disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
CN-101712776-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2010-05-26 CN disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed