SCHEMBL3794331

SCHEMBL3794331

CCC(C)c1c(C)ncnc1Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SELE P16581 1/20 0.32
VCAM1 P19320 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16624814 0.88 SELE (0.35) SELEVCAM1
SCHEMBL24227162 0.88 SELE (0.35) SELEVCAM1
SCHEMBL12228322 0.86 TSHR (0.31)
SCHEMBL19294654 0.86 TSHR (0.31)
SCHEMBL857517 0.79 PDE4A (0.30)
SCHEMBL19294662 0.79 TSHR (0.33) SELEVCAM1
SCHEMBL19294653 0.79 SELE (0.31) SELEVCAM1
SCHEMBL21919664 0.79
SCHEMBL20865971 0.76 NOS2 (0.35)
SCHEMBL20977931 0.74 SELE (0.34) SELEVCAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010135568-A1 BENZOXAZEPINES AS INHIBITORS OF MTOR AND THEIR USE TO TREAT CANCER EXELIXIS, INC. (US) 2010-11-25 WO disclosed