Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GSK3A | P49840 | 8/20 | 0.50 |
| ▸ | GSK3B | P49841 | 8/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16636652 | 0.85 | GSK3A (0.56) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL19220386 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL26286 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL20176213 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL16274020 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL14850663 | 0.83 | MEN1 (0.65) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL3062340 | 0.81 | GSK3A (0.62) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL186221 | 0.81 | MEN1 (0.62) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL14292315 | 0.80 | MAPT (0.51) | MEN1KMT2AGAAALDH1A1GSK3A | |
| SCHEMBL10601662 | 0.79 | GAA (1.00) | MEN1KMT2AGAAALDH1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081731-A2 | DERIVATIVES OF SYRINGOLIN A | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V (DE) | 2010-07-22 | — | — | WO | disclosed |