SCHEMBL20176213

SCHEMBL20176213

CCCCCCCN1C(=O)CSC1=S

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
GAA P10253 4/20 0.65
ALDH1A1 P00352 4/20 0.58
GSK3A P49840 8/20 0.50
GSK3B P49841 8/20 0.50
MGLL Q99685 4/20 0.46
PTGS1 P23219 3/20 0.46
PTGS2 P35354 3/20 0.46
FAAH O00519 3/20 0.46
PAX8 Q06710 1/20 0.45
RECQL P46063 3/20 0.41
MAPT P10636 2/20 0.40
THRB P10828 2/20 0.40
HTT P42858 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19220386 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL28886326 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL16274020 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL26286 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL14850663 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL186221 0.98 MEN1 (0.62) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL2788487 0.93 MEN1 (0.59) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL3138532 0.85 GSK3A (0.56) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL3794356 0.83 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL20176216 0.82 MAPT (0.54) MEN1KMT2AGAAALDH1A1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180144877-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOUND FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180144877-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOUND SLC9A1, SLC9A2, SLC26A3 MEN1 243/4885KMT2A 1601/4885GAA 2773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.