SCHEMBL26286

SCHEMBL26286

CCCCCCCCCCCCCCCCCCN1C(=O)CSC1=S

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
GAA P10253 4/20 0.65
ALDH1A1 P00352 4/20 0.58
GSK3A P49840 8/20 0.50
GSK3B P49841 8/20 0.50
MGLL Q99685 4/20 0.46
PTGS1 P23219 3/20 0.46
PTGS2 P35354 3/20 0.46
FAAH O00519 3/20 0.46
PAX8 Q06710 1/20 0.45
RECQL P46063 3/20 0.41
MAPT P10636 2/20 0.40
THRB P10828 2/20 0.40
HTT P42858 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19220386 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL28886326 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL16274020 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL14850663 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL20176213 1.00 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL186221 0.98 MEN1 (0.62) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL2788487 0.93 MEN1 (0.59) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL3138532 0.85 GSK3A (0.56) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL3794356 0.83 MEN1 (0.65) MEN1KMT2AGAAALDH1A1GSK3A
SCHEMBL20176216 0.82 MAPT (0.54) MEN1KMT2AGAAALDH1A1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110068529-B Characterization method of outer vesicle 中国科学院深圳先进技术研究院 2023-06-23 CN claimed
US-20230025694-A1 Silicone Hydrogel Based Fluorescent Assay and Contact Lens NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-01-26 US claimed
CN-109715066-B Silicone hydrogel based fluorescence assays and contact lenses 巴尔的摩马里兰大学 2022-04-05 CN claimed
US-20200229740-A1 Silicone Hydrogel Based Fluorescent Assay and Contact Lens NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-07-23 US claimed
CN-110068529-A A kind of characterizing method of outer vesica 中国科学院深圳先进技术研究院 2019-07-30 CN claimed
EP-3487406-A1 SILICONE HYDROGEL BASED FLUORESCENT ASSAY AND CONTACT LENS University of Maryland, Baltimore (US) 2019-05-29 EP claimed
CN-109715066-A Fluoremetry and haptic lens based on siloxanes aquogel 巴尔的摩马里兰大学 2019-05-03 CN claimed
EP-3307243-A1 DIAGNOSTIC TEST FOR EARLY STAGE CANCER The Board of Regents of The University of Texas System (US) 2018-04-18 EP claimed
WO-2018017842-A1 SILICONE HYDROGEL BASED FLUORESCENT ASSAY AND CONTACT LENS UNIVERSITY OF MARYLAND, BALTIMORE (US) 2018-01-25 WO claimed
WO-2016201064-A1 DIAGNOSTIC TEST FOR EARLY STAGE CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-12-15 WO claimed
WO-2005047481-A2 NOVEL SEQUENCES ENCODING HAPATITIS C VIRUS GLYCOPROTEINS PROGENICS PHARMACEUTICALS, INC. (US) 2005-05-26 WO claimed
EP-0738330-A4 METHODS FOR USING RESONANCE ENERGY TRANSFER-BASED ASSAY OF HIV-1 ENVELOPE CLYCOPROTEIN-MEDIATED MEMBRANE FUSION, AND KITS FOR PRACTICING SAME PROGENICS PHARM INC (US) 2002-10-30 EP claimed
US-6468763-B1 Optical detection of transmembrane potential changes CALIPER TECHNOLOGIES CORP. 2002-10-22 US claimed
EP-1039834-A4 OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE IMARX PHARMACEUTICAL CORP (US) 2001-12-05 EP claimed
US-6261763-B1 CONTACTING SAMPLE WITH A TEST AGENT, CLUSTER DETERMINANT CELLS AND ENVELOPE GLYCOPROTEIN CELLS TO DETERMINE THE AGENTS ABILITY TO INHIBIT CELL FUSION; CELLS WERE LABELED WITH DIFFERENT DYES ALLOWING RESONANCE ENERGY TRANSFER PROGENICS PHARMACEUTICALS, INC. 2001-07-17 US claimed
EP-1039834-A1 OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE IMARX PHARMACEUTICAL CORP. (US) 2000-10-04 EP claimed
US-6123923-A ADMINISTERING A PATIENT A CONTRAST AGENT CONTAINING A STABILIZER, A PHOTOACTIVE AGENT, A GASEOUS PRECURSOR SUCH AS PERFLUORINATED COMPOUND OR GAS OR BOTH, AND SCANNING THE PATIENT USING ULTRASOUND IMAGING AND OPTICAL IMAGING IMARX PHARMACEUTICAL CORP. (US) 2000-09-26 US claimed
WO-1999030620-A1 OPTOACOUSTIC CONTRAST AGENTS AND METHODS FOR THEIR USE IMARX PHARMACEUTICAL CORP. (US) 1999-06-24 WO claimed
EP-0738330-A1 METHODS FOR USING RESONANCE ENERGY TRANSFER-BASED ASSAY OF HIV-1 ENVELOPE CLYCOPROTEIN-MEDIATED MEMBRANE FUSION, AND KITS FOR PRACTICING SAME PROGENICS PHARMACEUTICALS, INC. (US) 1996-10-23 EP claimed
WO-1995016789-A1 METHODS FOR USING RESONANCE ENERGY TRANSFER-BASED ASSAY OF HIV-1 ENVELOPE CLYCOPROTEIN-MEDIATED MEMBRANE FUSION, AND KITS FOR PRACTICING SAME PROGENICS PHARMACEUTICALS, INC. (US) 1995-06-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230025694-A1 Silicone Hydrogel Based Fluorescent Assay and Contact Lens CD44, CRYAA, IGFBP1 MEN1 901/4885KMT2A 4319/4885GAA 1822/4885
US-20200229740-A1 Silicone Hydrogel Based Fluorescent Assay and Contact Lens CD44, CRYAA, IGFBP1 MEN1 901/4885KMT2A 4319/4885GAA 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.