Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795178 | 1.00 | CCR1 (0.42) | CCR1CYP3A4MMEROCK2ROCK1 | |
| SCHEMBL3800894 | 0.87 | MMP12 (0.46) | CCR1CYP3A4 | |
| SCHEMBL3800888 | 0.87 | MMP12 (0.46) | CCR1CYP3A4 | |
| SCHEMBL2440907 | 0.87 | MMP12 (0.46) | CCR1CYP3A4 | |
| SCHEMBL2440911 | 0.87 | MMP12 (0.46) | CCR1CYP3A4 | |
| SCHEMBL2433140 | 0.87 | CCR1 (0.41) | CCR1CYP3A4 | |
| SCHEMBL2435448 | 0.85 | CSNK1E (0.42) | ROCK2ROCK1 | |
| SCHEMBL3800006 | 0.84 | ROCK1 (0.47) | CCR1MMEROCK2ROCK1 | |
| SCHEMBL3800008 | 0.84 | ROCK1 (0.47) | CCR1MMEROCK2ROCK1 | |
| SCHEMBL3804480 | 0.84 | ROCK1 (0.47) | CCR1MMEROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140194349-A1 | HIV Protease Inhibiting Compounds | ABBVIE INC. (US) | 2014-07-10 | — | — | US | disclosed |
| EP-2266971-A2 | Hiv protease inhibiting compounds | Abbott Laboratories (US) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194349-A1 | HIV Protease Inhibiting Compounds | SERPINB1, HPN, DNPEP | CCR1 2263/4885CYP3A4 764/4885MME 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.