Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | EPOR | P19235 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536546 | 0.85 | CPA3 (0.53) | CPA3ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL19384899 | 0.85 | CPA3 (0.53) | CPA3ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL536547 | 0.85 | CPA3 (0.53) | CPA3ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL6849355 | 0.84 | FOLH1 (0.50) | CPA3ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8765293 | 0.84 | FOLH1 (0.50) | CPA3ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8765302 | 0.84 | FOLH1 (0.50) | CPA3ALDH1A1LMNAPOLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL3025758 | 0.83 | CPA3 (0.51) | CPA3ALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL3025760 | 0.83 | CPA3 (0.51) | CPA3ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL3791586 | 0.83 | EPOR (0.47) | CPA3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19100080 | 0.83 | MEN1 (0.49) | CPA3MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170054-A2 | TARGETING CONJUGATES COMPRISING ACTIVE AGENTS ENCAPSULATED IN CYCLODEXTRIN-CONTAINING POLYMERS | Capsutech Ltd. (IL) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009001364-A2 | TARGETING CONJUGATES COMPRISING ACTIVE AGENTS ENCAPSULATED IN CYCLODEXTRIN-CONTAINING POLYMERS | CAPSUTECH LTD (IL) | 2008-12-31 | — | — | WO | disclosed |