Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765293 | 1.00 | FOLH1 (0.50) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8765302 | 1.00 | FOLH1 (0.50) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7126845 | 0.90 | ALDH1A1 (0.48) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8764783 | 0.86 | ALDH1A1 (0.52) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL8764792 | 0.86 | ALDH1A1 (0.52) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7363077 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL10333560 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3795262 | 0.84 | CPA3 (0.51) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL7275088 | 0.83 | ALDH1A1 (0.52) | FOLH1ALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL3791586 | 0.83 | EPOR (0.47) | FOLH1ALDH1A1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390358-A4 | AMINO ACID DERIVATIVES OF TRIPTOLIDE COMPOUNDS AS IMMUNE MODULATORS AND ANTICANCER AGENT | PHARMAGENESIS INC (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1390358-A1 | AMINO ACID DERIVATIVES OF TRIPTOLIDE COMPOUNDS AS IMMUNE MODULATORS AND ANTICANCER AGENT | PHARMAGENESIS, INC. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002074759-A1 | AMINO ACID DERIVATIVES OF TRIPTOLIDE COMPOUNDS AS IMMUNE MODULATORS AND ANTICANCER AGENT | PHARMAGENESIS, INC. (US) | 2002-09-26 | — | — | WO | disclosed |